Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 N-6022 0件: ---1件: 299
2 N-acetylsulfanilyl chloride 0件: ---4件: 36, 51, 96, 97
3 Nabilone 1件: NABILONE1件: D05099 2件: CNR1,
CNR2 💬
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬2件: 6, 13
4 Nabiximols 1件: Nabiximols1件: D09317 --1件: 13
5 NADH 1件: NADH---1件: 302
6 Nadolol 1件: Nadolol1件: D00432 2件: ADRB1,
ADRB2 💬
11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
7 Nalbuphine 2件: Nalbuphine; NALBUPHINE HYDROCHLORIDE2件: D00843 ,
D08246
3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 85
8 Nalmefene 1件: Nalmefene1件: D05111 3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
9 Naloxone 2件: Naloxone; NALOXONE HYDROCHLORIDE2件: D01340 ,
D08249
3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 6, 226
10 Naltrexone 2件: Naltrexone; Naltrexone Hydrochloride2件: D02095 ,
D05113
3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
11 Namilumab 2件: MT203; NAMILUMAB---1件: 46
12 Nandrolone 1件: Nandrolone1件: D08250 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 60, 85
13 Nandrolone decanoate 1件: Nandrolone Decanoate1件: D00955 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 60, 85
14 Naproxen 5件: Naprosyn; NAPROXEN; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: D00118 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271
15 Narsoplimab 2件: MASP-2 antibody; Narsoplimab1件: D11531 1件: MASP2 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬4件: 64, 66, 109, 222
16 Natalizumab 2件: Natalizumab; Tysabri1件: D06886 1件: ITGA4 💬14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬6件: 13, 15, 25, 46, 63, 96
17 Natural Killer Cell 1件: NK Cells---1件: 26
18 Nebicapone 1件: Nebicapone---1件: 6
19 Nebivolol 1件: Nebivolol1件: D05127 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167
20 Neflamapimod 1件: Neflamapimod1件: D10959 4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬
62件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬1件: 8
21 Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222
22 Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen 1件: Nimenrix---2件: 50, 61
23 Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222
24 Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen 1件: Nimenrix---2件: 50, 61
25 Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222
26 Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen 1件: Nimenrix---2件: 50, 61
27 Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222
28 Neisseria meningitidis group Y capsular polysaccharide tetanus toxoid conjugate antigen 1件: Nimenrix---2件: 50, 61
29 Neisseria meningitidis serogroup b fhbp fusion protein antigen 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222
30 Neisseria meningitidis serogroup b nada protein antigen 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222
31 Neisseria meningitidis serogroup b nhba fusion protein antigen 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222
32 Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222
33 Nelfinavir 1件: Nelfinavir2件: D00899 ,
D08259
--3件: 49, 265, 331
34 Nelotanserin 1件: Nelotanserin1件: D09645 1件: HTR2A 💬5件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
35 Nemolizumab 1件: Nemolizumab1件: D11080 1件: IL31RA 💬1件: Cytokine-cytokine receptor interaction 💬1件: 51
36 Neomycin 1件: Neomycin1件: D08260 --3件: 96, 97, 296
37 Neopterin 1件: Neopterin---1件: 65
38 Neostigmine 1件: Neostigmine1件: D08261 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬1件: 11
39 Neramexane 1件: Neramexane---1件: 13
40 Neridronic Acid 1件: Neridronic Acid---1件: 6
41 Nerispirdine 1件: Nerispirdine---1件: 13
42 Nerve Growth Factor 1件: Nerve Growth Factor---3件: 3, 53, 90
43 Nesiritide 0件: 1件: D05147 1件: NPR1 💬10件: Aldosterone synthesis and secretion, Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 46, 58
44 Nevanimibe 1件: Nevanimibe1件: D11300 --2件: 75, 81
45 Nevirapine 1件: Nevirapine1件: D00435 --1件: 265
46 NGX267 1件: NGX267---1件: 53
47 Niacin 2件: Niacin; Nicotinic acid1件: D00049 --4件: 6, 78, 79, 265
48 Nicardipine 1件: Nicardipine2件: D00617 ,
D08270
4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 70, 86
49 Niclosamide 1件: Niclosamide1件: D00436 --2件: 46, 97
50 Nicotinamide 4件: Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
51 Nicotinamide riboside 1件: Nicotinamide Riboside---4件: 2, 6, 18, 191
52 Nicotine 2件: NICOTINE; Nicotine gum3件: D03365 ,
D05156 ,
D05157
16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬
7件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases 💬3件: 6, 13, 84
53 Nifedipine 1件: Nifedipine1件: D00437 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 50, 81
54 Nifurtimox 1件: Nifurtimox1件: D00833 --1件: 65
55 Nilotinib 2件: Nilotinib; Tasigna1件: D08953 4件: ABL1,
KIT,
PDGFRA,
PDGFRB 💬
33件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬5件: 6, 8, 34, 51, 86
56 Nilvadipine 1件: Nilvadipine1件: D01908 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 90
57 Nimesulide 1件: Nimesulide1件: D01049 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46
58 Nintedanib 2件: NINTEDANIB; Ofev1件: D10481 8件: FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬
34件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬5件: 51, 85, 89, 227, 228
59 Nipocalimab 1件: Nipocalimab1件: D11666 --5件: 11, 46, 49, 53, 61
60 Nitazoxanide 1件: Nitazoxanide1件: D02486 --2件: 96, 97
61 Nitisinone 2件: NITISINONE; Orfadin1件: D05177 1件: HPD 💬5件: Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬3件: 6, 164, 241
62 Nitrate 1件: Nitrate1件: D02313 --3件: 58, 113, 299
63 Nitric Oxide 3件: INOmax; NITRIC OXIDE; Nitrosyl1件: D00074 --16件: 6, 13, 46, 58, 85, 86, 96, 97, 98, 210, 222, 226, 251, 294, 299, 321
64 Nitrite 1件: Nitrite---3件: 58, 86, 299
65 Nitrofurantoin 1件: Nitrofurantoin1件: D00439 --1件: 13
66 Nitrogen 1件: Nitrogen1件: D00083 --6件: 5, 6, 17, 171, 211, 299
67 Nitroglycerin 2件: Nitroglycerin; Nitroglycerine1件: D00515 --2件: 46, 51
68 Nitroprusside 2件: Nitroprusside; SODIUM NITROPRUSSIDE1件: D00614 --1件: 51
69 Nitrous oxide 1件: Nitrous Oxide1件: D00102 --1件: 34
70 Nivolumab 1件: Nivolumab1件: D10316 1件: PDCD1 💬3件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159
71 NNZ-2591 1件: NNZ-2591---1件: 201
72 Nomacopan 2件: COVERSIN; NOMACOPAN1件: D11473 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 62, 109, 162
73 Nomegestrol 1件: Nomegestrol1件: D07222 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13
74 Nomegestrol acetate 1件: Nomegestrol acetate1件: D08281 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13
75 Norepinephrine 1件: Norepinephrine2件: D00076 ,
D05206
9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬
14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 22
76 Norethisterone 3件: Norethindrone; Ortho-novum; Ortho-Novum 7772件: D00182 ,
D00953
1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬4件: 13, 46, 49, 299
77 Norgestimate 1件: Norgestimate1件: D05209 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 299
78 Nortriptyline 2件: Nortriptyline; Nortriptyline hydrochloride2件: D00816 ,
D08288
2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226
79 norUrsodeoxycholic acid 2件: Norucholic acid; NorUrsodeoxycholic Acid---2件: 93, 94
80 Nusinersen 2件: NUSINERSEN; Spinraza1件: D10881 --1件: 3