Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 DRD1 💬 10件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Apomorphine 💬 Apomorphine 3件: 5, 6, 7 💬
2 DRD1 💬 10件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dopamine 💬 Dopamine 4件: 6, 7, 74, 299 💬
3 DRD2 💬 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Apomorphine 💬 Apomorphine 3件: 5, 6, 7 💬
4 DRD2 💬 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dopamine 💬 Dopamine 4件: 6, 7, 74, 299 💬
5 DRD3 💬 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine 4件: 6, 7, 74, 299 💬
6 DRD4 💬 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine 4件: 6, 7, 74, 299 💬
7 DRD5 💬 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine 4件: 6, 7, 74, 299 💬
8 MAPT 💬 4件: MAPK signaling pathway, Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Flortaucipir F 18 💬 Flortaucipir 3件: 5, 7, 127 💬
9 ROCK1 💬 20件: cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Axon guidance, Focal adhesion, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer Fasudil 💬 Fasudil 4件: 2, 5, 7, 51 💬
10 SNAP25 💬 2件: Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A 14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
11 ROCK2 💬 21件: cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Axon guidance, Focal adhesion, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, Lipid and atherosclerosis Fasudil 💬 Fasudil 4件: 2, 5, 7, 51 💬