Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept [2] ABATACEPT; ORENCIA[1] Abatacept 💬[2] CD80,
CD86 💬
[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen [4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] Acetaminophen 💬[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Acetate [1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
4 Adalimumab [7] Adalimumab; Amgevita; Cyltezo; Hulio; HUMIRA; Hyrimoz; Imraldi[1] Adalimumab 💬[1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
5 Aldosterone [1] Aldosterone[1] Aldosterone 💬[1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[1] 222 💬
6 Aliskiren [1] Aliskiren[1] Aliskiren 💬[1] REN 💬[3] Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[3] 66, 167, 222 💬
7 Amoxicillin [4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin[2] Amoxicillin ,
Amoxicillin 💬
--[9] 6, 19, 46, 63, 84, 96, 97, 222, 299 💬
8 Angiotensin II [2] Angiotensin; Angiotensin II[2] Angiotensin II ,
Angiotensin II 💬
[2] AGTR1,
AGTR2 💬
[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224 💬
9 Apixaban [2] Apixaban; Eliquis[1] Apixaban 💬[1] F10 💬[1] Complement and coagulation cascades 💬[1] 222 💬
10 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Lipitor[1] Atorvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
11 Atrasentan [1] ATRASENTAN---[3] 66, 218, 222 💬
12 Avacopan [1] Avacopan[1] Avacopan 💬[1] C5AR1 💬[6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬[3] 43, 44, 222 💬
13 Bardoxolone [1] Bardoxolone[1] Bardoxolone 💬--[7] 66, 67, 84, 85, 86, 218, 222 💬
14 Bardoxolone methyl [1] BARDOXOLONE METHYL[1] Bardoxolone methyl 💬--[7] 66, 67, 84, 85, 86, 218, 222 💬
15 Basiliximab [2] Basiliximab; Simulect[1] Basiliximab 💬[1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 50, 66, 97, 222, 228 💬
16 Belimumab [2] BELIMUMAB; BENLYSTA[1] Belimumab 💬[1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
17 Bleselumab [1] Bleselumab[1] Bleselumab 💬[1] CD40 💬[17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[1] 222 💬
18 Bortezomib [3] Bortezomib; Bortezomib Accord; VELCADE[1] Bortezomib 💬[1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
19 Butyric Acid [4] Butanoic acid; Butyrate; Butyric Acid; Sodium Butyrate---[7] 34, 46, 51, 97, 156, 222, 291 💬
20 Calcium [2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
21 CCX-140 [0] ---[1] 222 💬
22 Cefadroxil [0] [2] Cefadroxil ,
Cefadroxil 💬
--[2] 222, 240 💬
23 Chlorambucil [1] Chlorambucil[1] Chlorambucil 💬--[1] 222 💬
24 Cholesterol [1] Cholesterol[1] Cholesterol 💬--[6] 8, 19, 90, 160, 222, 310 💬
25 Clarithromycin [1] Clarithromycin[1] Clarithromycin 💬--[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
26 Corticotropin [5] ACTH; ACTHar; Adrenocorticotropic Hormone; Corticotrophin; Corticotropin[1] Corticotropin 💬[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
27 Creatinine [1] Creatinine[1] Creatinine 💬--[5] 2, 46, 60, 70, 222 💬
28 CXA-10 [1] CXA-10---[2] 86, 222 💬
29 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan[2] Cyclophosphamide ,
Cyclophosphamide 💬
--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
30 Cyclosporine [10] Ciclosporin; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
31 Dalteparin [2] Dalteparin; Fragmin---[1] 222 💬
32 Dapagliflozin [2] Dapagliflozin; Forxiga[1] Dapagliflozin 💬[1] SLC5A2 💬-[7] 19, 49, 66, 67, 86, 88, 222 💬
33 Dexamethasone [5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex[1] Dexamethasone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
34 Diphenhydramine [2] Diphenhydramine; Diphenhydramine hydrochloride[1] Diphenhydramine 💬[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
35 Eculizumab [2] ECULIZUMAB; Soliris[1] Eculizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222 💬
36 Enalapril [2] Enalapril; Enalapril Maleate[1] Enalapril 💬[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222 💬
37 Evolocumab [2] EVOLOCUMAB; Repatha[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222 💬
38 Felzartamab [1] Felzartamab---[2] 66, 222 💬
39 Filgotinib [2] FILGOTINIB; Jyseleca[1] Filgotinib 💬[1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[6] 46, 53, 96, 97, 222, 271 💬
40 Fluvastatin [1] Fluvastatin[1] Fluvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222 💬
41 Fosfomycin [1] Fosfomycin[1] Fosfomycin 💬--[3] 96, 97, 222 💬
42 Fresolimumab [2] Fresolimumab; GC1008[1] Fresolimumab 💬[3] TGFB1,
TGFB2,
TGFB3 💬
[35] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[3] 51, 85, 222 💬
43 Galactose [2] D-Galactose; Galactose[1] Galactose 💬--[1] 222 💬
44 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
45 Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen [2] ACT-HIB; ActHIB---[5] 14, 61, 62, 66, 222 💬
46 Hydroxychloroquine [3] Hydroxychloroquine; Hydroxychloroquine Sulfate; Plaquenil[1] Hydroxychloroquine 💬--[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
47 Interleukin-1 alpha, human recombinant [1] None---[18] 6, 46, 51, 65, 66, 84, 85, 96, 97, 140, 161, 171, 222, 231, 246, 271, 299, 337 💬
48 Iohexol [2] Iohexol; OMNIPAQUE[1] Iohexol 💬--[3] 19, 67, 222 💬
49 Iptacopan [1] Iptacopan[1] Iptacopan 💬[1] CFB 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[5] 61, 62, 66, 109, 222 💬
50 Irbesartan [2] Aprovel; Irbesartan[1] Irbesartan 💬[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 66, 167, 168, 222 💬
51 L-Glutamine [2] Glutamine; L-Glutamine[1] Glutamine 💬--[8] 87, 89, 96, 97, 113, 222, 245, 299 💬
52 Lanraplenib [1] Lanraplenib[1] Lanraplenib 💬--[2] 53, 222 💬
53 Lansoprazole [1] Lansoprazole[1] Lansoprazole 💬[2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299 💬
54 Levamisole [1] Levamisole[1] Levamisole 💬--[4] 60, 61, 62, 222 💬
55 Levothyroxine [2] Levothyroxine; Thyroxine[1] Levothyroxine 💬[2] THRA,
THRB 💬
[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222 💬
56 Lisinopril [2] Lisinopril; Zestril[2] Lisinopril ,
Lisinopril 💬
[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
57 Losartan [3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] Losartan 💬[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
58 Losmapimod [1] LOSMAPIMOD[1] Losmapimod 💬[4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬
[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[2] 113, 222 💬
59 Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine [1] Menveo---[6] 11, 13, 61, 62, 66, 222 💬
60 Meningococcal polysaccharide vaccine group A [2] Menveo; Nimenrix[1] Meningococcal polysaccharide vaccine group A 💬--[7] 11, 13, 50, 61, 62, 66, 222 💬
61 Meningococcal polysaccharide vaccine group C [2] Menveo; Nimenrix[1] Meningococcal polysaccharide vaccine group C 💬--[7] 11, 13, 50, 61, 62, 66, 222 💬
62 Meningococcal polysaccharide vaccine group W-135 [2] Menveo; Nimenrix---[7] 11, 13, 50, 61, 62, 66, 222 💬
63 Meningococcal polysaccharide vaccine group Y [2] Menveo; Nimenrix---[7] 11, 13, 50, 61, 62, 66, 222 💬
64 Methylprednisolone [4] Medrol; Methylprednisolon; METHYLPREDNISOLONE; Methylprednisolone acetate[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
65 Methylprednisone [1] Methylprednisone---[4] 46, 66, 85, 222 💬
66 Mizoribine [2] BREDININ; Mizoribine[1] Mizoribine 💬[2] IMPDH1,
IMPDH2 💬
[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
67 Monomethyl fumarate [2] Bafiertam; Monomethyl fumarate[1] Monomethyl fumarate 💬--[16] 13, 35, 40, 46, 49, 50, 51, 60, 65, 66, 107, 162, 222, 224, 226, 299 💬
68 Mycophenolate mofetil [3] CELLCEPT; Mycophenolate Mofetil; Mycophenolate mofetil TEVA[1] Mycophenolate mofetil 💬[2] IMPDH1,
IMPDH2 💬
[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
69 Mycophenolic acid [5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[1] Mycophenolic acid 💬[2] IMPDH1,
IMPDH2 💬
[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
70 Narsoplimab [2] MASP-2 antibody; Narsoplimab[1] Narsoplimab 💬[1] MASP2 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[4] 64, 66, 109, 222 💬
71 Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen [1] Menveo---[6] 11, 13, 61, 62, 66, 222 💬
72 Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen [1] Menveo---[6] 11, 13, 61, 62, 66, 222 💬
73 Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen [1] Menveo---[6] 11, 13, 61, 62, 66, 222 💬
74 Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen [1] Menveo---[6] 11, 13, 61, 62, 66, 222 💬
75 Neisseria meningitidis serogroup b fhbp fusion protein antigen [1] Bexsero---[6] 11, 13, 61, 62, 66, 222 💬
76 Neisseria meningitidis serogroup b nada protein antigen [1] Bexsero---[6] 11, 13, 61, 62, 66, 222 💬
77 Neisseria meningitidis serogroup b nhba fusion protein antigen [1] Bexsero---[6] 11, 13, 61, 62, 66, 222 💬
78 Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle [1] Bexsero---[6] 11, 13, 61, 62, 66, 222 💬
79 Nitric Oxide [3] INOmax; Nitric Oxide; Nitrosyl[1] Nitric oxide 💬--[12] 6, 58, 85, 86, 88, 97, 210, 222, 251, 294, 299, 321 💬
80 Obinutuzumab [2] GAZYVARO; OBINUTUZUMAB[1] Obinutuzumab 💬[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[4] 43, 44, 49, 222 💬
81 Panax notoginseng root [1] Sanqi[1] Panax notoginseng root 💬--[1] 222 💬
82 Pegcetacoplan [2] Aspaveli; Pegcetacoplan[1] Pegcetacoplan 💬[1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[4] 2, 61, 62, 222 💬
83 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬--[12] 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
84 Perindopril [2] Coversyl; Perindopril[1] Perindopril 💬[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 58, 113, 167, 222 💬
85 Pirfenidone [2] Esbriet; Pirfenidone[1] Pirfenidone 💬[6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬
[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
86 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
87 Prednisolone acetate [1] PREDNISOLONE ACETATE[1] Prednisolone acetate 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 222 💬
88 Prednisone [3] PREDNISONA; Prednisone; RAYOS[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
89 Resiniferatoxin [0] ---[5] 11, 46, 65, 222, 240 💬
90 Rituximab [6] MabThera; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA[1] Rituximab 💬[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
91 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[1] Rosiglitazone 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265 💬
92 Sacubitril [2] Entresto; Sacubitril[1] Sacubitril 💬[1] MME 💬[4] Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬[2] 58, 222 💬
93 Sinomenine [1] Sinomenine---[2] 46, 222 💬
94 Sirolimus [3] RAPAMUNE; Rapamycin; Sirolimus[1] Sirolimus 💬[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
95 Sparsentan [1] SPARSENTAN[1] Sparsentan 💬[2] AGTR1,
EDNRA 💬
[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
96 Streptococcus pneumoniae type 1 capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
97 Streptococcus pneumoniae type 14 capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
98 Streptococcus pneumoniae type 18c capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
99 Streptococcus pneumoniae type 19a capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
100 Streptococcus pneumoniae type 19f capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
101 Streptococcus pneumoniae type 23f capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
102 Streptococcus pneumoniae type 3 capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
103 Streptococcus pneumoniae type 4 capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
104 Streptococcus pneumoniae type 5 capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
105 Streptococcus pneumoniae type 6b capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
106 Streptococcus pneumoniae type 7f capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
107 Streptococcus pneumoniae type 9v capsular polysaccharide antigen [2] Pneumovax 23; Prevenar 13---[6] 13, 14, 46, 50, 96, 222 💬
108 Sulfate ion [1] Sulfate---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
109 Tacrolimus [2] Prograf; Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬
[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
110 Tetracosactide [4] Cosyntropin; SYNACTHEN DEPOT; Tetracosactide; Tetracosactrin[1] Cosyntropin 💬[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 78, 83, 113, 145, 222 💬
111 Tripterygium wilfordii whole [2] Tripterygium; Tripterygium Wilfordii---[8] 46, 66, 67, 96, 162, 222, 224, 271 💬
112 TRU-015 [1] TRU-015---[3] 46, 49, 222 💬
113 Valproic acid [3] Valproate; VALPROATE SODIUM; Valproic Acid[1] Valproic acid 💬[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
114 Valsartan [3] Diovan; Entresto; VALSARTAN[1] Valsartan 💬[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224 💬
115 Vitamin D [3] Calciferol; Cod liver oil; Vitamin D---[20] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 💬
116 Voclosporin [1] Voclosporin[1] Voclosporin 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 49, 222 💬
117 Zanubrutinib [1] Zanubrutinib[1] Zanubrutinib 💬[1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 13, 63, 222, 300, 331 💬