Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
2 TUBB3 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
3 TUBB3 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
4 TUBB3 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
5 TUBB3 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
6 TUBB3 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
7 TUBB3 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
8 TUBB4A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
9 TUBB4A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
10 TUBB4A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
11 TUBB4A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
12 TUBB4A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
13 TUBB4A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
14 TUBB4B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
15 TUBB4B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
16 TUBB4B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
17 TUBB4B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
18 TUBB4B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
19 TUBB4B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
20 CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction Montelukast 💬 Montelukast [8] 6, 13, 46, 61, 63, 85, 98, 228 💬
21 HRH3 💬 [1] Neuroactive ligand-receptor interaction Bavisant 💬 Bavisant [1] 6 💬
22 HRH3 💬 [1] Neuroactive ligand-receptor interaction Pitolisant 💬 Pitolisant [3] 6, 113, 193 💬
23 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
24 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
25 CHRM1 💬 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
26 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Tropicamide 💬 Tropicamide [1] 6 💬
27 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
28 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Pilocarpine 💬 Pilocarpine [3] 6, 53, 299 💬
29 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Fesoterodine 💬 Fesoterodine [1] 6 💬
30 CHRM2 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
31 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
32 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
33 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Pilocarpine 💬 Pilocarpine [3] 6, 53, 299 💬
34 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin 💬 Darifenacin [2] 6, 13 💬
35 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Fesoterodine 💬 Fesoterodine [1] 6 💬
36 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Solifenacin 💬 Solifenacin [3] 6, 13, 53 💬
37 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
38 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Tropicamide 💬 Tropicamide [1] 6 💬
39 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
40 CHRM4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
41 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
42 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
43 CHRM5 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
44 CHRNA1 💬 [2] Virion - Lyssavirus, Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
45 CHRNA2 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
46 CHRNA3 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
47 CHRNA4 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
48 CHRNA4 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline [3] 6, 18, 53 💬
49 CHRNA5 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
50 CHRNA7 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Nicotine addiction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
51 CHRNB1 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
52 CHRNB2 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
53 CHRNB2 💬 [4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline [3] 6, 18, 53 💬
54 CHRNB3 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
55 CHRNB4 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
56 CHRND 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
57 CHRNE 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
58 CHRNG 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
59 CLCN2 💬 [1] Mineral absorption Lubiprostone 💬 Lubiprostone [4] 6, 13, 290, 299 💬
60 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Nabilone 💬 Nabilone [3] 6, 13, 127 💬
61 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Cannabidiol 💬 Cannabidiol [20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
62 CNR2 💬 [1] Neuroactive ligand-receptor interaction Nabilone 💬 Nabilone [3] 6, 13, 127 💬
63 CNR2 💬 [1] Neuroactive ligand-receptor interaction Cannabidiol 💬 Cannabidiol [20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
64 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Entacapone 💬 Entacapone [2] 6, 17 💬
65 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Tolcapone 💬 Tolcapone [3] 6, 28, 127 💬
66 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Opicapone 💬 Opicapone [1] 6 💬
67 ADORA1 💬 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
68 ADORA1 💬 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
69 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Adenosine 💬 Adenosine [3] 13, 58, 65 💬
70 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
71 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
72 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Adenosine phosphate 💬 Adenosine phosphate [1] 46 💬
73 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Istradefylline 💬 Istradefylline [1] 6 💬
74 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Regadenoson 💬 Regadenoson [1] 58 💬
75 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Preladenant 💬 Preladenant [1] 6 💬
76 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Tozadenant 💬 Tozadenant [1] 6 💬
77 ADORA2A 💬 [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Regadenoson 💬 Regadenoson [1] 58 💬
78 CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Sargramostim 💬 Sargramostim [7] 6, 28, 60, 62, 96, 229, 285 💬
79 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Filgrastim 💬 Filgrastim [35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
80 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
81 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Dipivefrin 💬 Dipivefrin [1] 6 💬
82 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Midodrine 💬 Midodrine [3] 6, 17, 58 💬
83 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Terazosin 💬 Terazosin [1] 6 💬
84 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
85 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Dipivefrin 💬 Dipivefrin [1] 6 💬
86 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Midodrine 💬 Midodrine [3] 6, 17, 58 💬
87 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Terazosin 💬 Terazosin [1] 6 💬
88 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
89 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Silodosin 💬 Silodosin [2] 6, 13 💬
90 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Dipivefrin 💬 Dipivefrin [1] 6 💬
91 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Midodrine 💬 Midodrine [3] 6, 17, 58 💬
92 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Terazosin 💬 Terazosin [1] 6 💬
93 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Clonidine 💬 Clonidine [4] 6, 65, 70, 78 💬
94 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Clozapine 💬 Clozapine [1] 6 💬
95 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Dexmedetomidine 💬 Dexmedetomidine [14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
96 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
97 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Dipivefrin 💬 Dipivefrin [1] 6 💬
98 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Yohimbine 💬 Yohimbine [1] 6 💬
99 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Clonidine 💬 Clonidine [4] 6, 65, 70, 78 💬
100 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Clozapine 💬 Clozapine [1] 6 💬
101 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Dexmedetomidine 💬 Dexmedetomidine [14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
102 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
103 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Dipivefrin 💬 Dipivefrin [1] 6 💬
104 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Yohimbine 💬 Yohimbine [1] 6 💬
105 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Clonidine 💬 Clonidine [4] 6, 65, 70, 78 💬
106 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Clozapine 💬 Clozapine [1] 6 💬
107 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Dexmedetomidine 💬 Dexmedetomidine [14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
108 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
109 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Dipivefrin 💬 Dipivefrin [1] 6 💬
110 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Yohimbine 💬 Yohimbine [1] 6 💬
111 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Nadolol 💬 Nadolol [1] 6 💬
112 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
113 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Dipivefrin 💬 Dipivefrin [1] 6 💬
114 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Propranolol 💬 Propranolol [6] 6, 158, 167, 227, 278, 296 💬
115 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Nadolol 💬 Nadolol [1] 6 💬
116 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
117 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Tulobuterol 💬 Tulobuterol [1] 6 💬
118 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Dipivefrin 💬 Dipivefrin [1] 6 💬
119 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Clenbuterol 💬 Clenbuterol [5] 1, 2, 6, 13, 256 💬
120 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Propranolol 💬 Propranolol [6] 6, 158, 167, 227, 278, 296 💬
121 ADRB3 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
122 ADRB3 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Dipivefrin 💬 Dipivefrin [1] 6 💬
123 ADRB3 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Propranolol 💬 Propranolol [6] 6, 158, 167, 227, 278, 296 💬
124 ADRB3 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Mirabegron 💬 Mirabegron [4] 6, 13, 53, 226 💬
125 ACE 💬 [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy Captopril 💬 Captopril [8] 6, 17, 46, 86, 96, 97, 107, 271 💬
126 DDC 💬 [9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa [7] 6, 13, 17, 90, 140, 164, 201 💬
127 DDC 💬 [9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Benserazide 💬 Benserazide [1] 6 💬
128 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
129 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
130 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
131 NQO1 💬 [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin 💬 Warfarin [11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
132 DPP4 💬 [1] Protein digestion and absorption Sitagliptin 💬 Sitagliptin [4] 6, 75, 233, 299 💬
133 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
134 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Flupentixol 💬 Flupentixol [1] 97 💬
135 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Apomorphine 💬 Apomorphine [3] 5, 6, 7 💬
136 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
137 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Pergolide 💬 Pergolide [1] 6 💬
138 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dexpramipexole 💬 Dexpramipexole [1] 2 💬
139 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Tavapadon 💬 Tavapadon [1] 6 💬
140 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Foslevodopa 💬 Foslevodopa [1] 6 💬
141 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
142 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Haloperidol 💬 Haloperidol [1] 8 💬
143 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Chlorpromazine 💬 Chlorpromazine [1] 254 💬
144 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Risperidone 💬 Risperidone [5] 8, 156, 179, 187, 206 💬
145 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Olanzapine 💬 Olanzapine [2] 2, 8 💬
146 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pimozide 💬 Pimozide [1] 2 💬
147 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Metoclopramide 💬 Metoclopramide [2] 46, 51 💬
148 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Cabergoline 💬 Cabergoline [3] 6, 74, 75 💬
149 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Flupentixol 💬 Flupentixol [1] 97 💬
150 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
151 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Sulpiride 💬 Sulpiride [2] 6, 70 💬
152 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Terguride 💬 Terguride [2] 51, 86 💬
153 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Trifluoperazine maleate 💬 Trifluoperazine [2] 283, 284 💬
154 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Domperidone 💬 Domperidone [5] 6, 13, 17, 51, 230 💬
155 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Iloperidone 💬 Iloperidone [1] 6 💬
156 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Bromocriptine 💬 Bromocriptine [2] 6, 74 💬
157 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pramipexole 💬 Pramipexole [3] 2, 6, 20 💬
158 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Rotigotine 💬 Rotigotine [1] 6 💬
159 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Piribedil 💬 Piribedil [1] 6 💬
160 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Melperone 💬 Melperone [1] 6 💬
161 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Apomorphine 💬 Apomorphine [3] 5, 6, 7 💬
162 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Buspirone 💬 Buspirone [2] 6, 51 💬
163 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Domperidone maleate 💬 Domperidone [5] 6, 13, 17, 51, 230 💬
164 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
165 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Lisuride 💬 Lisuride [2] 6, 86 💬
166 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pergolide 💬 Pergolide [1] 6 💬
167 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Quetiapine 💬 Quetiapine [2] 6, 13 💬
168 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Ropinirole 💬 Ropinirole [4] 2, 6, 74, 309 💬
169 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Tiapride 💬 Tiapride [1] 8 💬
170 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Trifluoperazine 💬 Trifluoperazine [2] 283, 284 💬
171 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pardoprunox 💬 Pardoprunox [1] 6 💬
172 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dexpramipexole 💬 Dexpramipexole [1] 2 💬
173 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pridopidine 💬 Pridopidine [3] 2, 6, 8 💬
174 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Cariprazine 💬 Cariprazine [1] 21 💬
175 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Foslevodopa 💬 Foslevodopa [1] 6 💬
176 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
177 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
178 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Pramipexole 💬 Pramipexole [3] 2, 6, 20 💬
179 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Piribedil 💬 Piribedil [1] 6 💬
180 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
181 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Lisuride 💬 Lisuride [2] 6, 86 💬
182 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Ropinirole 💬 Ropinirole [4] 2, 6, 74, 309 💬
183 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Pardoprunox 💬 Pardoprunox [1] 6 💬
184 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Foslevodopa 💬 Foslevodopa [1] 6 💬
185 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
186 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Clozapine 💬 Clozapine [1] 6 💬
187 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Pramipexole 💬 Pramipexole [3] 2, 6, 20 💬
188 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
189 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Lisuride 💬 Lisuride [2] 6, 86 💬
190 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Ropinirole 💬 Ropinirole [4] 2, 6, 74, 309 💬
191 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Foslevodopa 💬 Foslevodopa [1] 6 💬
192 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
193 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
194 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Tavapadon 💬 Tavapadon [1] 6 💬
195 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Foslevodopa 💬 Foslevodopa [1] 6 💬
196 ABAT 💬 [7] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
197 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
198 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
199 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
200 TUBB 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
201 TUBB 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
202 TUBB 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
203 TUBB 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
204 TUBB 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
205 TUBB 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
206 F8 💬 [1] Complement and coagulation cascades Desmopressin 💬 Desmopressin [6] 6, 64, 72, 75, 225, 288 💬
207 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
208 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
209 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Valiloxybate 💬 Valiloxybate [1] 6 💬
210 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
211 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
212 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Etomidate 💬 Etomidate [1] 6 💬
213 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
214 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
215 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
216 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
217 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
218 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
219 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
220 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
221 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
222 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
223 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
224 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
225 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
226 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
227 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
228 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
229 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
230 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
231 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
232 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
233 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
234 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
235 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
236 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
237 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
238 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
239 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
240 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
241 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
242 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
243 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
244 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
245 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
246 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
247 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
248 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
249 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
250 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
251 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
252 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
253 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
254 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
255 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
256 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
257 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
258 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
259 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
260 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
261 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
262 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
263 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
264 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
265 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
266 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
267 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
268 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
269 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
270 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
271 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
272 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
273 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
274 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
275 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
276 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
277 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
278 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
279 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
280 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
281 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
282 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
283 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
284 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
285 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
286 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
287 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
288 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
289 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
290 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
291 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
292 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
293 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
294 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
295 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
296 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
297 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
298 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
299 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
300 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
301 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
302 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
303 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
304 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
305 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
306 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
307 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
308 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
309 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
310 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
311 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
312 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
313 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
314 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
315 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
316 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
317 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
318 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
319 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
320 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
321 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
322 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
323 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
324 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
325 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
326 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
327 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
328 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
329 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
330 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
331 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
332 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
333 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
334 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
335 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
336 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
337 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
338 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
339 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
340 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
341 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
342 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
343 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
344 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
345 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
346 GAD1 💬 [7] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
347 GAD2 💬 [7] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
348 ABL1 💬 [11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
349 ABL1 💬 [11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis Saracatinib 💬 Saracatinib [3] 6, 89, 272 💬
350 GLP1R 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion Exenatide 💬 Exenatide [6] 6, 17, 72, 78, 193, 233 💬
351 GLP1R 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion Liraglutide 💬 Liraglutide [3] 6, 75, 193 💬
352 GLP1R 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion Lixisenatide 💬 Lixisenatide [1] 6 💬
353 GLP1R 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion Semaglutide 💬 Semaglutide [1] 6 💬
354 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
355 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
356 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
357 GRIA1 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
358 GRIA1 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Talampanel 💬 Talampanel [2] 2, 6 💬
359 GRIA1 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Perampanel 💬 Perampanel [3] 2, 6, 144 💬
360 GRIA2 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
361 GRIA2 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Talampanel 💬 Talampanel [2] 2, 6 💬
362 GRIA2 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Perampanel 💬 Perampanel [3] 2, 6, 144 💬
363 GRIA3 💬 [13] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
364 GRIA3 💬 [13] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Talampanel 💬 Talampanel [2] 2, 6 💬
365 GRIA3 💬 [13] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Perampanel 💬 Perampanel [3] 2, 6, 144 💬
366 GRIA4 💬 [10] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
367 GRIA4 💬 [10] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Talampanel 💬 Talampanel [2] 2, 6 💬
368 GRIA4 💬 [10] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Perampanel 💬 Perampanel [3] 2, 6, 144 💬
369 GRIK1 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
370 GRIK2 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
371 GRIK3 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
372 GRIK4 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
373 GRIK5 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
374 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
375 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [2] 6, 206 💬
376 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine [4] 6, 8, 13, 127 💬
377 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Ketamine 💬 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215 💬
378 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
379 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
380 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate 💬 Acamprosate [2] 6, 206 💬
381 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine 💬 Amantadine [4] 6, 8, 13, 127 💬
382 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Ketamine 💬 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215 💬
383 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
384 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
385 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate 💬 Acamprosate [2] 6, 206 💬
386 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine 💬 Amantadine [4] 6, 8, 13, 127 💬
387 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Ketamine 💬 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215 💬
388 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
389 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
390 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [2] 6, 206 💬
391 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine [4] 6, 8, 13, 127 💬
392 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Ketamine 💬 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215 💬
393 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
394 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
395 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [2] 6, 206 💬
396 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine [4] 6, 8, 13, 127 💬
397 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Ketamine 💬 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215 💬
398 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
399 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone 💬 Hydrocortisone [10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
400 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone cypionate 💬 Hydrocortisone cypionate [3] 6, 81, 83 💬
401 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone succinate 💬 Hydrocortisone succinate [3] 6, 81, 83 💬
402 GUCY2C 💬 [2] Purine metabolism, Metabolic pathways Linaclotide 💬 Linaclotide [2] 6, 97 💬
403 HCRTR1 💬 [1] Neuroactive ligand-receptor interaction Suvorexant 💬 Suvorexant [3] 5, 6, 13 💬
404 HCRTR2 💬 [1] Neuroactive ligand-receptor interaction Suvorexant 💬 Suvorexant [3] 5, 6, 13 💬
405 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Lovastatin 💬 Lovastatin [11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
406 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Simvastatin 💬 Simvastatin [21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
407 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Rosuvastatin 💬 Rosuvastatin [11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
408 HPD 💬 [5] Ubiquinone and other terpenoid-quinone biosynthesis, Tyrosine metabolism, Phenylalanine metabolism, Metabolic pathways, Biosynthesis of cofactors Nitisinone 💬 Nitisinone [3] 6, 164, 241 💬
409 HRH1 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels Doxepin 💬 Doxepin [1] 6 💬
410 HRH2 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gastric acid secretion Famotidine 💬 Famotidine [6] 6, 46, 61, 86, 98, 107 💬
411 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
412 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Buspirone 💬 Buspirone [2] 6, 51 💬
413 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Pardoprunox 💬 Pardoprunox [1] 6 💬
414 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
415 HTR1B 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Zolmitriptan 💬 Zolmitriptan [1] 6 💬
416 HTR1D 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Zolmitriptan 💬 Zolmitriptan [1] 6 💬
417 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Clozapine 💬 Clozapine [1] 6 💬
418 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
419 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Iloperidone 💬 Iloperidone [1] 6 💬
420 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Quetiapine 💬 Quetiapine [2] 6, 13 💬
421 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Nelotanserin 💬 Nelotanserin [1] 6 💬
422 HTR2B 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Iloperidone 💬 Iloperidone [1] 6 💬
423 HTR2C 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Clozapine 💬 Clozapine [1] 6 💬
424 HTR2C 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Agomelatine 💬 Agomelatine [1] 6 💬
425 HTR2C 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Iloperidone 💬 Iloperidone [1] 6 💬
426 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
427 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
428 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
429 TUBB8 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
430 TUBB8 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
431 TUBB8 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
432 TUBB8 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
433 TUBB8 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
434 TUBB8 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
435 TUBB2B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
436 TUBB2B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
437 TUBB2B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
438 TUBB2B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
439 TUBB2B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
440 TUBB2B 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
441 KCNA4 💬 [2] Cortisol synthesis and secretion, Cushing syndrome Dalfampridine 💬 Dalfampridine [5] 3, 4, 6, 13, 14 💬
442 KCNC3 💬 [1] Spinocerebellar ataxia Dalfampridine 💬 Dalfampridine [5] 3, 4, 6, 13, 14 💬
443 KCND2 💬 [1] Serotonergic synapse Dalfampridine 💬 Dalfampridine [5] 3, 4, 6, 13, 14 💬
444 KCND3 💬 [1] Spinocerebellar ataxia Dalfampridine 💬 Dalfampridine [5] 3, 4, 6, 13, 14 💬
445 KCNJ11 💬 [3] Insulin secretion, GnRH secretion, Type II diabetes mellitus Repaglinide 💬 Repaglinide [4] 6, 21, 46, 299 💬
446 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
447 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Masitinib 💬 Masitinib [6] 2, 5, 6, 13, 46, 96 💬
448 MAOA 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Moclobemide 💬 Moclobemide [1] 6 💬
449 MAOA 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Iproniazid 💬 Iproniazid [1] 6 💬
450 MAOA 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
451 MAOA 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phenelzine 💬 Phenelzine [1] 6 💬
452 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Iproniazid 💬 Iproniazid [1] 6 💬
453 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Selegiline 💬 Selegiline [1] 6 💬
454 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
455 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phenelzine 💬 Phenelzine [1] 6 💬
456 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline 💬 Rasagiline [6] 2, 5, 6, 17, 58, 66 💬
457 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Safinamide 💬 Safinamide [2] 6, 17 💬
458 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline tartrate 💬 Rasagiline [6] 2, 5, 6, 17, 58, 66 💬
459 MAPT 💬 [4] MAPK signaling pathway, Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Flortaucipir F 18 💬 Flortaucipir [3] 5, 7, 127 💬
460 MAPT 💬 [4] MAPK signaling pathway, Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Gosuranemab 💬 Gosuranemab [1] 5 💬
461 MAPT 💬 [4] MAPK signaling pathway, Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Hydromethylthionine mesylate 💬 Hydromethylthionine mesylate [1] 127 💬
462 MAP3K5 💬 [20] Platinum drug resistance, MAPK signaling pathway, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Apoptosis, Tight junction, TNF signaling pathway, Thermogenesis, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Alcoholic liver disease, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Selonsertib 💬 Selonsertib [1] 86 💬
463 NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption Fludrocortisone 💬 Fludrocortisone [3] 6, 17, 81 💬
464 ACHE 💬 [2] Glycerophospholipid metabolism, Cholinergic synapse Rivastigmine 💬 Rivastigmine [3] 5, 6, 13 💬
465 ACHE 💬 [2] Glycerophospholipid metabolism, Cholinergic synapse Galantamine 💬 Galantamine [2] 6, 127 💬
466 ACHE 💬 [2] Glycerophospholipid metabolism, Cholinergic synapse Donepezil 💬 Donepezil [9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
467 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Agomelatine 💬 Agomelatine [1] 6 💬
468 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Ramelteon 💬 Ramelteon [3] 6, 8, 46 💬
469 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
470 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Agomelatine 💬 Agomelatine [1] 6 💬
471 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Ramelteon 💬 Ramelteon [3] 6, 8, 46 💬
472 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
473 NFE2L2 💬 [7] Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Omaveloxolone 💬 Omaveloxolone [1] 18 💬
474 ATP4A 💬 [4] Oxidative phosphorylation, Metabolic pathways, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
475 ATP4B 💬 [4] Oxidative phosphorylation, Metabolic pathways, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
476 OPRD1 💬 [3] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Nalmefene 💬 Nalmefene [1] 6 💬
477 OPRD1 💬 [3] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Naltrexone 💬 Naltrexone [13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
478 OPRD1 💬 [3] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Oxycodone 💬 Oxycodone [5] 6, 13, 70, 226, 298 💬
479 OPRD1 💬 [3] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Naloxone 💬 Naloxone [2] 6, 226 💬
480 OPRK1 💬 [1] Neuroactive ligand-receptor interaction Nalmefene 💬 Nalmefene [1] 6 💬
481 OPRK1 💬 [1] Neuroactive ligand-receptor interaction Naltrexone 💬 Naltrexone [13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
482 OPRK1 💬 [1] Neuroactive ligand-receptor interaction Oxycodone 💬 Oxycodone [5] 6, 13, 70, 226, 298 💬
483 OPRK1 💬 [1] Neuroactive ligand-receptor interaction Naloxone 💬 Naloxone [2] 6, 226 💬
484 OPRM1 💬 [3] Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Nalmefene 💬 Nalmefene [1] 6 💬
485 OPRM1 💬 [3] Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Naltrexone 💬 Naltrexone [13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
486 OPRM1 💬 [3] Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Oxycodone 💬 Oxycodone [5] 6, 13, 70, 226, 298 💬
487 OPRM1 💬 [3] Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Naloxone 💬 Naloxone [2] 6, 226 💬
488 OPRM1 💬 [3] Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Remifentanil 💬 Remifentanil [2] 6, 70 💬
489 OXTR 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway Oxytocin 💬 Oxytocin [7] 6, 72, 127, 168, 193, 206, 226 💬
490 PDE2A 💬 [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
491 PDE2A 💬 [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
492 PDE3A 💬 [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
493 PDE3A 💬 [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
494 PDE3B 💬 [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
495 PDE3B 💬 [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
496 PDE4A 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
497 PDE4A 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
498 PDE4B 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
499 PDE4B 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
500 PDE4C 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
501 PDE4C 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
502 PDE4D 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
503 PDE4D 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
504 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
505 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
506 PDGFRA 💬 [20] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
507 PDGFRB 💬 [19] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
508 PPARG 💬 [11] PPAR signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Pioglitazone 💬 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
509 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
510 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
511 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
512 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
513 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
514 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
515 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
516 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
517 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
518 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
519 AVPR2 💬 [3] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulated water reabsorption Desmopressin 💬 Desmopressin [6] 6, 64, 72, 75, 225, 288 💬
520 CHRNA9 💬 [2] Neuroactive ligand-receptor interaction, Chemical carcinogenesis - receptor activation Nicotine 💬 Nicotine [3] 6, 13, 84 💬
521 PRKAA1 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
522 PRKAA2 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
523 CACNA2D3 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
524 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
525 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
526 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
527 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
528 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
529 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
530 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
531 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
532 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
533 PRL 💬 [5] Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Prolactin signaling pathway Cabergoline 💬 Cabergoline [3] 6, 74, 75 💬
534 PRL 💬 [5] Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Prolactin signaling pathway Bromocriptine 💬 Bromocriptine [2] 6, 74 💬
535 PSMB5 💬 [8] Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
536 PSMB5 💬 [8] Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases Carfilzomib 💬 Carfilzomib [1] 28 💬
537 PSMB5 💬 [8] Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
538 CHRNA10 💬 [1] Neuroactive ligand-receptor interaction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
539 PTGS1 💬 [5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Acetaminophen 💬 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
540 PTGS2 💬 [22] Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Acetaminophen 💬 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
541 SCN1A 💬 [1] Dopaminergic synapse Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
542 SCN1A 💬 [1] Dopaminergic synapse Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
543 SCN1A 💬 [1] Dopaminergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
544 SCN1A 💬 [1] Dopaminergic synapse Zonisamide 💬 Zonisamide [1] 6 💬
545 SCN1A 💬 [1] Dopaminergic synapse Flecainide 💬 Flecainide [1] 6 💬
546 SCN1A 💬 [1] Dopaminergic synapse Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
547 SCN1A 💬 [1] Dopaminergic synapse Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
548 SCN2A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
549 SCN2A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
550 SCN2A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
551 SCN2A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
552 SCN2A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
553 SCN2A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
554 SCN2A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
555 SCN3A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
556 SCN3A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
557 SCN3A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
558 SCN3A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
559 SCN3A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
560 SCN3A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
561 SCN3A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
562 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
563 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
564 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
565 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Zonisamide 💬 Zonisamide [1] 6 💬
566 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Flecainide 💬 Flecainide [1] 6 💬
567 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
568 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
569 SCN9A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
570 SCN9A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
571 SCN9A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
572 SCN9A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
573 SCN9A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
574 SCN9A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
575 SCN9A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
576 SLC6A1 💬 [2] Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
577 SLC6A2 💬 [1] Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
578 SLC6A2 💬 [1] Synaptic vesicle cycle Atomoxetine 💬 Atomoxetine [4] 6, 8, 13, 17 💬
579 SLC6A2 💬 [1] Synaptic vesicle cycle Doxepin 💬 Doxepin [1] 6 💬
580 SLC6A2 💬 [1] Synaptic vesicle cycle Duloxetine 💬 Duloxetine [2] 6, 13 💬
581 SLC6A2 💬 [1] Synaptic vesicle cycle Nortriptyline 💬 Nortriptyline [2] 6, 226 💬
582 SLC6A2 💬 [1] Synaptic vesicle cycle Venlafaxine 💬 Venlafaxine [3] 6, 13, 46 💬
583 SLC6A2 💬 [1] Synaptic vesicle cycle Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
584 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Armodafinil 💬 Armodafinil [3] 6, 13, 84 💬
585 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
586 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
587 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion [5] 8, 18, 21, 96, 171 💬
588 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
589 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Sertraline 💬 Sertraline [2] 6, 206 💬
590 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Paroxetine 💬 Paroxetine [4] 6, 13, 46, 85 💬
591 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram [7] 6, 8, 13, 18, 46, 98, 127 💬
592 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Doxepin 💬 Doxepin [1] 6 💬
593 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Duloxetine 💬 Duloxetine [2] 6, 13 💬
594 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Escitalopram 💬 Escitalopram [4] 2, 6, 13, 46 💬
595 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Nortriptyline 💬 Nortriptyline [2] 6, 226 💬
596 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Venlafaxine 💬 Venlafaxine [3] 6, 13, 46 💬
597 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Vortioxetine 💬 Vortioxetine [1] 6 💬
598 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
599 SLC10A2 💬 [1] Bile secretion Elobixibat 💬 Elobixibat [1] 6 💬
600 SLC12A2 💬 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection Bumetanide 💬 Bumetanide [2] 6, 158 💬
601 SLC12A2 💬 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection Furosemide 💬 Furosemide [2] 6, 86 💬
602 SLC18A2 💬 [7] Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Tetrabenazine 💬 Tetrabenazine [1] 8 💬
603 SLC18A2 💬 [7] Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Valbenazine 💬 Valbenazine [1] 8 💬
604 SLC18A2 💬 [7] Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Deutetrabenazine 💬 Deutetrabenazine [1] 8 💬
605 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A [14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
606 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Rimabotulinumtoxin B 💬 Botulinum toxin type B [4] 2, 6, 13, 51 💬
607 SNCA 💬 [3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Prasinezumab 💬 Prasinezumab [1] 6 💬
608 SOD1 💬 [8] Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species Tofersen 💬 Tofersen [1] 2 💬
609 SRC 💬 [42] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Saracatinib 💬 Saracatinib [3] 6, 89, 272 💬
610 SRD5A2 💬 [3] Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer Finasteride 💬 Finasteride [1] 6 💬
611 ABCC8 💬 [3] ABC transporters, Insulin secretion, Type II diabetes mellitus Repaglinide 💬 Repaglinide [4] 6, 21, 46, 299 💬
612 TUBB2A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
613 TUBB2A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
614 TUBB2A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
615 TUBB2A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
616 TUBB2A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
617 TUBB2A 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
618 UGCG 💬 [2] Sphingolipid metabolism, Metabolic pathways Venglustat 💬 Venglustat [3] 6, 19, 67 💬
619 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Cholecalciferol 💬 Cholecalciferol [24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
620 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Dihydrotachysterol 💬 Dihydrotachysterol [2] 6, 85 💬
621 TRPV1 💬 [2] Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels Capsaicin 💬 Capsaicin [3] 6, 86, 226 💬
622 XDH 💬 [6] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome Allopurinol 💬 Allopurinol [7] 6, 46, 57, 60, 66, 96, 97 💬
623 XDH 💬 [6] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome Febuxostat 💬 Febuxostat [3] 2, 6, 13 💬
624 CA2 💬 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
625 CA4 💬 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
626 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
627 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
628 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
629 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
630 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
631 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
632 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
633 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
634 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
635 VKORC1 💬 [3] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors Warfarin 💬 Warfarin [11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
636 ALDH5A1 💬 [3] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, Metabolic pathways Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
637 TAS1R2 💬 [2] Taste transduction, Carbohydrate digestion and absorption Aspartame 💬 Aspartame [4] 6, 13, 67, 86 💬
638 TUBB1 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
639 TUBB1 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
640 TUBB1 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
641 TUBB1 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
642 TUBB1 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
643 TUBB1 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
644 TAS1R3 💬 [2] Taste transduction, Carbohydrate digestion and absorption Aspartame 💬 Aspartame [4] 6, 13, 67, 86 💬
645 CASP9 💬 [35] Platinum drug resistance, p53 signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Apoptosis - multiple species, VEGF signaling pathway, Thyroid hormone signaling pathway, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Legionellosis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Small cell lung cancer, Non-small cell lung cancer, Viral myocarditis, Lipid and atherosclerosis Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
646 TUBB6 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Paclitaxel 💬 Paclitaxel [2] 46, 85 💬
647 TUBB6 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [7] 2, 42, 46, 56, 93, 210, 266 💬
648 TUBB6 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vinblastine 💬 Vinblastine [2] 34, 65 💬
649 TUBB6 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Vincristine 💬 Vincristine [4] 26, 34, 65, 331 💬
650 TUBB6 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
651 TUBB6 💬 [10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
652 PDE5A 💬 [3] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
653 PDE5A 💬 [3] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
654 PDE5A 💬 [3] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway Tadalafil 💬 Tadalafil [7] 6, 51, 75, 84, 86, 113, 210 💬
655 PDE5A 💬 [3] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway Sildenafil 💬 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
656 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
657 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Zonisamide 💬 Zonisamide [1] 6 💬
658 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
659 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Zonisamide 💬 Zonisamide [1] 6 💬
660 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Valproic acid 💬 Valproic acid [14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
661 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Zonisamide 💬 Zonisamide [1] 6 💬
662 CHRNA6 💬 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction Nicotine 💬 Nicotine [3] 6, 13, 84 💬
663 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
664 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
665 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
666 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
667 CACNA2D4 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
668 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Valiloxybate 💬 Valiloxybate [1] 6 💬
669 KEAP1 💬 [6] Ubiquitin mediated proteolysis, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Dimethyl fumarate 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
670 SV2A 💬 [1] ECM-receptor interaction Levetiracetam 💬 Levetiracetam [5] 2, 4, 6, 13, 307 💬
671 NR1H4 💬 [1] Bile secretion Ursodiol 💬 Ursodeoxycholic acid [14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬