Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 7-beta-Hydroxyepiandrosterone [1] 7-beta-Hydroxyepiandrosterone---[1] 6 💬
2 8-hydroxy-2'-deoxyguanosine [1] 8-OHdG---[1] 6 💬
3 Acamprosate [1] Acamprosate[1] Acamprosate 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206 💬
4 Acetaminophen [4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] Acetaminophen 💬[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
5 Acetate [1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
6 Acetic acid C-11 [1] 11C-ACETATE---[4] 6, 13, 86, 88 💬
7 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-acetylcysteine[1] Acetylcysteine 💬--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
8 ACR325 [1] ACR325---[1] 6 💬
9 Activated charcoal [1] Carbon---[6] 6, 85, 86, 96, 97, 158 💬
10 Ademetionine [2] SAM-e; SAMe[1] Ademetionine 💬--[2] 6, 93 💬
11 Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins [1] HB-adMSCs---[5] 2, 6, 13, 14, 46 💬
12 Agomelatine [1] Agomelatine[1] Agomelatine 💬[3] HTR2C,
MTNR1A,
MTNR1B 💬		[6] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
13 Alanine [2] Alanine; L-alanine[1] Alanine 💬--[4] 6, 13, 298, 299 💬
14 Albendazole [2] Albendazole; Eskazole[1] Albendazole 💬--[12] 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127 💬
15 Alirinetide [2] GM604; GM608---[2] 2, 6 💬
16 Allopurinol [2] Allopurinol; ALLOPURINOL SODIUM[1] Allopurinol 💬[1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
17 Altropane [1] Altropane---[1] 6 💬
18 Amantadine [3] AMANTADINE; AMANTADINE HYDROCHLORIDE; GOCOVRI[1] Amantadine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127 💬
19 Ambroxol [1] Ambroxol[1] Ambroxol 💬--[2] 6, 19 💬
20 Ammonia [1] Ammonia[1] Ammonia solution, strong 💬--[2] 6, 296 💬
21 Amoxicillin [4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin[2] Amoxicillin ,
Amoxicillin 💬		--[9] 6, 19, 46, 63, 84, 96, 97, 222, 299 💬
22 Ampicillin [1] ABPC[1] Ampicillin 💬--[5] 2, 6, 13, 84, 299 💬
23 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
24 anle138b [1] Anle138b---[1] 6 💬
25 Apigenin [1] Apigenin---[2] 6, 97 💬
26 Aplindore [1] Aplindore---[1] 6 💬
27 Apomorphine [4] APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride[1] Apomorphine 💬[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
28 Aripiprazole [1] Aripiprazole[1] Aripiprazole 💬[4] DRD2,
DRD3,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206 💬
29 Armodafinil [2] Armodafinil; MODAFINIL[1] Armodafinil 💬[1] SLC6A3 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84 💬
30 Aspartame [0] [1] Aspartame 💬[2] TAS1R2,
TAS1R3 💬		[2] Carbohydrate digestion and absorption, Taste transduction 💬[4] 6, 13, 67, 86 💬
31 Atomoxetine [2] Atomoxetine; Strattera[1] Atomoxetine 💬[1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
32 AV-101 [1] AV-101---[2] 6, 86 💬
33 Azathioprine [3] Azathioprine; Azatioprina; Imuran[1] Azathioprine 💬--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
34 AZD-0328 [0] ---[1] 6 💬
35 Bavisant [1] Bavisant[1] Bavisant 💬[1] HRH3 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6 💬
36 Benserazide [1] BENSERAZIDE[1] Benserazide 💬[1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
37 Benzofuran [1] Benzofuran---[1] 6 💬
38 BIA [1] BIA---[2] 6, 86 💬
39 Botulinum toxin type A [8] Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] Botulinum toxin type A 💬[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
40 Botulinum toxin type B [3] Botulinum toxin type B; MYOBLOC; NEUROBLOC[1] Rimabotulinumtoxin B 💬[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51 💬
41 Bromocriptine [1] BROMOCRIPTINE[1] Bromocriptine 💬[2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 74 💬
42 BTRX-246040 [1] BTRX-246040---[1] 6 💬
43 Bumetanide [1] Bumetanide[1] Bumetanide 💬[1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 158 💬
44 Buspirone [2] Buspirone; Buspirone Hydrochloride[1] Buspirone 💬[2] DRD2,
HTR1A 💬		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 51 💬
45 Butylphthalide [1] Butylphthalide---[4] 2, 6, 18, 22 💬
46 Cabergoline [3] CABERGOLINA; Cabergoline; DOSTINEX[1] Cabergoline 💬[2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75 💬
47 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine hydrate 💬		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
48 Calcium [2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
49 Cannabidiol [4] CANNABIDIOL; Epidiolex; Epidyolex; SATIVEX[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
50 Capsaicin [2] Capsaicin; Qutenza[1] Capsaicin 💬[1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226 💬
51 Captopril [1] Captopril[1] Captopril 💬[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[8] 6, 17, 46, 86, 96, 97, 107, 271 💬
52 Carbamazepine [1] Carbamazepine[1] Carbamazepine 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231 💬
53 Carbidopa [8] Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] Carbidopa 💬[1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
54 Carnosine [1] Carnosine---[2] 6, 13 💬
55 Ceftriaxone [1] CEFTRIAXONE[1] Ceftriaxone 💬--[4] 2, 6, 46, 97 💬
56 CEP-1347 [1] CEP-1347---[1] 6 💬
57 Chamomile [2] Chamomile; MATRICARIA FLOWER[1] German chamomile flower 💬--[2] 6, 97 💬
58 Chloride ion [1] Chloride---[28] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338 💬
59 Cholecalciferol [5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] Cholecalciferol 💬[1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
60 Citalopram [1] Citalopram[1] Citalopram 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
61 Citicoline [1] Citicolina[1] Citicoline 💬--[1] 6 💬
62 Clarithromycin [1] CLARITHROMYCIN[1] Clarithromycin 💬--[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
63 Clenbuterol [1] Clenbuterol[1] Clenbuterol 💬[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 1, 2, 6, 13, 256 💬
64 Clonazepam [1] Clonazepam[1] Clonazepam 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬
65 Clonidine [4] Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE[1] Clonidine 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78 💬
66 Clozapine [1] CLOZAPINE[1] Clozapine 💬[11] ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[8] Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬[1] 6 💬
67 Cobalt chloride [1] Ceretec---[1] 6 💬
68 Cocoa [2] Chocolate; Cocoa---[1] 6 💬
69 Creatine [1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201 💬
70 Crocin [1] Crocin---[1] 6 💬
71 Cultivated mushroom [1] Mushroom---[2] 6, 46 💬
72 Cyanocobalamin [2] Cianocobalamina; Vitamin B12[4] Cyanocobalamin ,
Cyanocobalamin Co 57 ,
Cyanocobalamin Co 58 ,
Cyanocobalamin Co 60 💬		--[5] 6, 13, 201, 229, 299 💬
73 D-Serine [1] D-Serine---[1] 6 💬
74 Dalfampridine [7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra[1] Dalfampridine 💬[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
75 Darifenacin [2] Darifenacin; Emselex[1] Darifenacin 💬[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13 💬
76 Deanol [1] Deanol[1] Deanol 💬--[1] 6 💬
77 Deferiprone [2] DEFERIPRONE; Ferriprox[1] Deferiprone 💬--[6] 2, 6, 18, 120, 122, 233 💬
78 Delorazepam [0] [1] Delorazepam 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 46, 97 💬
79 Desmopressin [5] DDAVP; Desmopressin; Desmopressin Acetate; Desmopressine; Minirin[1] Desmopressin 💬[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288 💬
80 Dexmedetomidine [4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[1] Dexmedetomidine 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
81 Dextromethorphan [4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[1] Dextromethorphan 💬[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
82 Dextrose, unspecified form [3] Dextrose; Glucose; Smofkabiven---[16] 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299 💬
83 Dichloroisoproterenol [0] ---[2] 6, 299 💬
84 Dihydroergotoxine [1] Dihydroergotoxine[1] Dihydroergotoxine 💬--[1] 6 💬
85 Dihydrotachysterol [0] [1] Dihydrotachysterol 💬[1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 6, 85 💬
86 Dipivefrin [2] Dipivefrin; Dipivefrine[1] Dipivefrin 💬[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
87 Dipraglurant [1] Dipraglurant---[1] 6 💬
88 Doconexent [2] Docosahexaenoic acid; Docosahexanoic Acid---[10] 6, 46, 48, 49, 90, 94, 113, 240, 299, 301 💬
89 Domperidone [1] Domperidone[2] Domperidone ,
Domperidone maleate 💬		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
90 Donepezil [3] Aricept; Donepezil; Donepezil hydrochloride[1] Donepezil 💬[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
91 Dopamine [2] Dopamina; Dopamine[1] Dopamine 💬[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299 💬
92 Doxepin [1] Doxepin[1] Doxepin 💬[3] HRH1,
SLC6A2,
SLC6A4 💬		[5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6 💬
93 Droxidopa [4] DOPS; Droxidopa; L-DOPS; Northera[1] Droxidopa 💬[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
94 Duloxetine [3] CYMBALTA; Duloxetine; Duloxetine hydrochloride[1] Duloxetine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
95 Edaravone [3] Edaravone; Methylphenylpyrazolone; Norphenazone[1] Edaravone 💬--[3] 2, 6, 22 💬
96 Eliprodil [1] Eliprodil---[1] 6 💬
97 Elobixibat [1] Elobixibat[1] Elobixibat 💬[1] SLC10A2 💬[1] Bile secretion 💬[1] 6 💬
98 Eltoprazine [1] ELTOPRAZINE---[1] 6 💬
99 Entacapone [5] COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo[1] Entacapone 💬[1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
100 EPI-589 [1] EPI-589---[2] 2, 6 💬
101 Epigallocatechin gallate [3] EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299 💬
102 Ergoloid mesylate [2] Dihydroergotoxine Mesylate; Ergoloid Mesylate---[2] 6, 206 💬
103 Erythromycin [1] Erythromycin[1] Erythromycin 💬--[5] 6, 36, 164, 228, 291 💬
104 Erythropoietin [4] Epoetin alfa; Epoetin beta; ERYTHROPOIETIN; NeoRecormon---[10] 2, 6, 13, 18, 22, 46, 47, 70, 95, 96 💬
105 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[1] Escitalopram 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
106 Eszopiclone [2] Eszopiclone; Zopiclone[1] Eszopiclone 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46 💬
107 Etomidate [1] Etomidate[1] Etomidate 💬[1] GABRA1 💬[6] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[1] 6 💬
108 Exametazime [1] Exametazime[1] Exametazime 💬--[1] 6 💬
109 Exenatide [3] BYDUREON; Byetta; EXENATIDE[1] Exenatide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
110 Famotidine [2] FAMOTIDINA; Famotidine[1] Famotidine 💬[1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107 💬
111 Febuxostat [1] Febuxostat[1] Febuxostat 💬[1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[3] 2, 6, 13 💬
112 Fesoterodine [1] Fesoterodine[1] Fesoterodine 💬[2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
113 Filgrastim [7] Filgrastim; Filgrastim Hexal; G-CSF; GRANULOCYTE COLONY STIMULATING FACTOR; Neupogen; TEVAGRASTIM; Zarzio[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
114 Finasteride [1] Finasteride[1] Finasteride 💬[1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6 💬
115 Fipamezole [1] Fipamezole---[2] 6, 17 💬
116 Flecainide [3] Flecainide; FLECAINIDE ACETATE; Flecainidum[1] Flecainide 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
117 Florbenazine F-18 [1] 18F-AV-133---[1] 6 💬
118 Florbetaben (18F) [2] FLORBETABEN (18F); Neuraceq---[1] 6 💬
119 Fludeoxyglucose (18F) [2] 18F-FDG; Fludeoxyglucose---[8] 5, 6, 7, 13, 84, 85, 127, 300 💬
120 Fludrocortisone [1] Fludrocortisone[1] Fludrocortisone 💬[1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
121 Flumazenil [1] Flumazenil[1] Flumazenil 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
122 Flutemetamol [1] Flutemetamol---[4] 5, 6, 7, 127 💬
123 Folic acid [5] Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE[1] Folic acid 💬--[6] 6, 41, 46, 49, 84, 296 💬
124 Foliglurax [1] Foliglurax---[1] 6 💬
125 Foscarbidopa [1] Foscarbidopa[1] Foscarbidopa 💬--[1] 6 💬
126 Foslevodopa [1] Foslevodopa[1] Foslevodopa 💬[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
127 Furosemide [2] Furosemide; Furosemide Injection[1] Furosemide 💬[1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 86 💬
128 Gabapentin [4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[1] Gabapentin 💬[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
129 Galantamine [2] GALANTAMINE; Galantamine hydrobromide[1] Galantamine 💬[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[2] 6, 127 💬
130 gamma-Hydroxybutyric acid [1] Oxybate---[2] 6, 149 💬
131 Ginkgo biloba [3] Ginkgo; Ginkgo biloba; Tanakan---[5] 6, 13, 18, 47, 90 💬
132 Glutathione [2] Glutathione; Reduced Glutathione[2] Glutathione ,
Oxiglutatione 💬		--[2] 6, 299 💬
133 Glycerin [2] Bee venom; Glycerol[1] Glycerin 💬--[5] 6, 13, 79, 316, 317 💬
134 Glycerol phenylbutyrate [3] Glycerol Phenylbutyrate; GT4P; Ravicti[1] Glycerol phenylbutyrate 💬--[3] 6, 251, 299 💬
135 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
136 GPI-1485 [0] ---[1] 6 💬
137 Grapefruit [1] Grapefruit---[5] 6, 46, 50, 83, 97 💬
138 Green tea leaf [4] Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract[1] Green tea leaf 💬--[4] 6, 17, 28, 46 💬
139 Guar gum [1] Guar gum[1] Guar gum 💬--[1] 6 💬
140 Heptaminol [1] Heptaminol[1] Heptaminol 💬--[1] 6 💬
141 Hydrocortisone [6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] Hydrocortisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
142 Hydrocortisone cypionate [1] Cortef[1] Hydrocortisone cypionate 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
143 Hydrocortisone succinate [2] HYDROCORTISONE HYDROGEN SUCCINATE; Solu-Cortef[1] Hydrocortisone succinate 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
144 Hydrogen [2] Dihydrogen; Hydrogen---[7] 5, 6, 17, 65, 83, 97, 226 💬
145 Idebenone [2] Idebenone; Raxone[1] Idebenone 💬--[6] 6, 8, 13, 18, 113, 302 💬
146 Iloperidone [1] Iloperidone[1] Iloperidone 💬[4] DRD2,
HTR2A,
HTR2B,
HTR2C 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 6 💬
147 Inosine [1] Inosine[1] Inosine 💬--[6] 2, 6, 13, 17, 85, 122 💬
148 Interleukin-1 alpha, human recombinant [1] None---[18] 6, 46, 51, 65, 66, 84, 85, 96, 97, 140, 161, 171, 222, 231, 246, 271, 299, 337 💬
149 Inulin [1] Inulin[1] Inulin 💬--[4] 6, 96, 156, 299 💬
150 Iodide I-123 [2] I 123; I-123---[2] 2, 6 💬
151 Ioflupane I-123 [3] DATSCAN; Ioflupane; Ioflupane I 123---[3] 2, 5, 6 💬
152 Ipratropium [1] Ipratropium---[2] 6, 86 💬
153 Iproniazid [1] IPRONIAZID[1] Iproniazid 💬[2] MAOA,
MAOB 💬		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
154 Isoflurane [1] Isoflurane[1] Isoflurane 💬--[1] 6 💬
155 Isoxaflutole [1] Balance---[5] 6, 11, 46, 81, 149 💬
156 Isradipine [1] Isradipine[1] Isradipine 💬[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
157 Istradefylline [1] ISTRADEFYLLINE[1] Istradefylline 💬[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
158 ITI-214 [1] ITI-214---[1] 6 💬
159 Josamycin [0] [1] Josamycin 💬--[2] 6, 13 💬
160 KDT-3594 [1] KDT-3594---[1] 6 💬
161 Ketamine [2] Ketamine; NMDA[1] Ketamine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 4, 6, 13, 70, 113, 156, 215 💬
162 KW-6356 [1] KW-6356---[1] 6 💬
163 Lactobacillus acidophilus [4] Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus[1] Lactomin 💬--[3] 6, 49, 97 💬
164 Lactobacillus casei [2] Fusion; Lactobacillus casei[1] Lactobacillus casei 💬--[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
165 Lactobacillus delbrueckii bulgaricus [1] Lactobacillus---[5] 6, 46, 51, 97, 299 💬
166 Lactobacillus plantarum [1] Lactobacillus plantarum---[3] 6, 97, 156 💬
167 Lactose [1] Lactose[2] Anhydrous lactose ,
Lactose 💬		--[6] 2, 6, 13, 97, 228, 310 💬
168 Lenomorelin [1] Ghrelin---[6] 6, 78, 193, 201, 202, 299 💬
169 Leptin [1] Leptin---[2] 6, 265 💬
170 Leucine [2] L-leucine; Leucine[1] Leucine 💬--[6] 6, 19, 65, 283, 284, 299 💬
171 Levetiracetam [2] KEPPRA; Levetiracetam[1] Levetiracetam 💬[1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
172 Levodopa [9] Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] Levodopa 💬[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
173 Levomefolic acid [1] L-methylfolate[1] Levomefolic acid 💬--[2] 6, 201 💬
174 Liatermin [2] Liatermin; R-metHuGDNF[1] Liatermin 💬--[1] 6 💬
175 Lidocaine [4] Aloe; Lidocaine; Lignocaine; Xylocaine[2] Lidocaine ,
Lidocaine hydrochloride monohydrate 💬		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
176 Linaclotide [1] Linaclotide[1] Linaclotide 💬[1] GUCY2C 💬[2] Metabolic pathways, Purine metabolism 💬[2] 6, 97 💬
177 Linoleic acid [1] Linoleic acid---[8] 2, 5, 6, 13, 76, 78, 256, 299 💬
178 Liraglutide [2] Liraglutide; Saxenda[1] Liraglutide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 6, 75, 193 💬
179 Lisuride [1] LISURIDE[1] Lisuride 💬[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
180 Lithium citrate [2] Lithium; LITHIUM CITRATE[1] Lithium citrate 💬--[5] 2, 5, 6, 7, 8 💬
181 Lixisenatide [1] Lixisenatide[1] Lixisenatide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
182 Lovastatin [1] Lovastatin[1] Lovastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
183 Lubiprostone [1] Lubiprostone[1] Lubiprostone 💬[1] CLCN2 💬[1] Mineral absorption 💬[4] 6, 13, 290, 299 💬
184 Magnesium [1] Magnesium---[19] 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298 💬
185 Magnesium oxide [1] Magnesium Oxide[1] Magnesium oxide 💬--[3] 6, 166, 291 💬
186 Maltodextrin [1] Maltodextrin[1] Maltodextrin 💬--[4] 6, 13, 96, 97 💬
187 Manganese citrate [1] Release---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299 💬
188 Mannitol [4] Aridol; Bronchitol; Mannite; Mannitol[1] Mannitol 💬--[7] 6, 13, 28, 60, 96, 113, 299 💬
189 Masitinib [1] Masitinib[1] Masitinib 💬[1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
190 Mavoglurant [1] Mavoglurant---[2] 6, 206 💬
191 MC-1 [0] ---[1] 6 💬
192 Medical Cannabis [3] Cannabis; Marijuana; Medical Cannabis---[7] 2, 6, 13, 19, 90, 96, 97 💬
193 Medium-chain triglycerides [3] Medium chain triglyceride; Smofkabiven; SMOFLipid---[5] 6, 66, 96, 296, 318 💬
194 Melatonin [2] Circadin; Melatonin[1] Melatonin 💬[2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
195 Melevodopa [1] Melevodopa[1] Melevodopa 💬--[1] 6 💬
196 Melperone [1] Melperone[1] Melperone 💬[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
197 Memantine [3] EBIXA; Memantine; MEMANTINE HYDROCHLORIDE[1] Memantine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
198 Mesdopetam [1] Mesdopetam---[1] 6 💬
199 Metformin [5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[1] Metformin 💬[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
200 Methylphenidate [3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[1] Methylphenidate 💬[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
201 Midazolam [2] Midazolam; Midazolam injection[1] Midazolam 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
202 Midodrine [2] Midodrine; MIDODRINE HYDROCHLORIDE[1] Midodrine 💬[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
203 Minocycline [3] Minocycline; Minocycline hydrochloride; Minomycin[1] Minocycline 💬--[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
204 Minodronic acid [2] Minodronate; Minodronic acid---[4] 6, 46, 93, 95 💬
205 Mirabegron [1] Mirabegron[1] Mirabegron 💬[1] ADRB3 💬[8] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
206 Mitoquinone [1] Mitoquinone---[3] 6, 13, 97 💬
207 Moclobemide [1] MOCLOBEMIDE[1] Moclobemide 💬[1] MAOA 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
208 Modafinil [2] MODAFINIL; Provigil[1] Modafinil 💬--[5] 6, 13, 49, 93, 113 💬
209 Montelukast [3] MONTELUKAST; MONTELUKAST SODIUM; Singulair[1] Montelukast 💬[1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228 💬
210 Moxifloxacin [2] Moxifloxacin; Moxifloxacin Hydrochloride[1] Moxifloxacin 💬--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
211 Muscimol [1] Muscimol---[1] 6 💬
212 Nabilone [1] Nabilone[1] Nabilone 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127 💬
213 Nadolol [1] Nadolol[1] Nadolol 💬[2] ADRB1,
ADRB2 💬		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
214 Nalmefene [1] Nalmefene[1] Nalmefene 💬[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
215 Naloxone [2] Naloxone; NALOXONE HYDROCHLORIDE[1] Naloxone 💬[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
216 Naltrexone [2] Naltrexone; Naltrexone Hydrochloride[1] Naltrexone 💬[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
217 Nebicapone [1] Nebicapone---[1] 6 💬
218 Nelotanserin [1] Nelotanserin[1] Nelotanserin 💬[1] HTR2A 💬[5] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
219 Neridronic Acid [1] Neridronic Acid---[1] 6 💬
220 Niacin [2] Niacin; Nicotinic acid[1] Niacin 💬--[3] 6, 78, 79 💬
221 Nicotinamide [3] Multivitamin; Niacinamide; NICOTINAMIDE[1] Niacinamide 💬--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
222 Nicotinamide riboside [1] Nicotinamide Riboside---[5] 2, 6, 18, 97, 191 💬
223 Nicotine [2] Nicotine; Nicotine gum[1] Nicotine 💬[16] CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬		[8] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬[3] 6, 13, 84 💬
224 Nilotinib [2] Nilotinib; Tasigna[1] Nilotinib 💬[4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
225 Nitisinone [2] NITISINONE; Orfadin[1] Nitisinone 💬[1] HPD 💬[5] Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬[3] 6, 164, 241 💬
226 Nitric Oxide [3] INOmax; Nitric Oxide; Nitrosyl[1] Nitric oxide 💬--[12] 6, 58, 85, 86, 88, 97, 210, 222, 251, 294, 299, 321 💬
227 Nitrogen [1] Nitrogen[1] Nitrogen 💬--[5] 5, 6, 17, 211, 299 💬
228 Nortriptyline [2] Nortriptyline; Nortriptyline hydrochloride[1] Nortriptyline 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
229 Omeprazole [4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[1] Omeprazole 💬[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
230 Ondansetron [1] Ondansetron[1] Ondansetron 💬[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107 💬
231 Opicapone [2] Ongentys; OPICAPONE[1] Opicapone 💬[1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
232 Oxaloacetic acid [1] Oxaloacetate---[2] 6, 11 💬
233 Oxybuprocaine [1] Oxybuprocaine[1] Oxybuprocaine 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
234 Oxybutynin [1] Oxybutynin[1] Oxybutynin 💬[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
235 Oxycodone [2] OXYCODONE; OXYCODONE HYDROCHLORIDE[1] Oxycodone 💬[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
236 Oxygen [3] Medical air; Nitrogen; Oxygen[1] Oxygen 💬--[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330 💬
237 Oxytocin [2] Oxytocin; Syntocinon[1] Oxytocin 💬[1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226 💬
238 Pardoprunox [1] Pardoprunox[1] Pardoprunox 💬[3] DRD2,
DRD3,
HTR1A 💬		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
239 Paroxetine [1] Paroxetine[1] Paroxetine 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
240 Perampanel [2] Fycompa; Perampanel[1] Perampanel 💬[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
241 Pergolide [1] PERGOLIDE[1] Pergolide 💬[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
242 Phenelzine [1] Nardil[1] Phenelzine 💬[2] MAOA,
MAOB 💬		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
243 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; PHENYLBUTYRATE; Sodium phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬
244 Phosphate ion [1] Phosphate---[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299 💬
245 Piclozotan [1] Piclozotan---[1] 6 💬
246 Pilocarpine [2] Pilocarpine; Pilocarpine Hydrochloride[1] Pilocarpine 💬[2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
247 Pimavanserin [1] Pimavanserin---[1] 6 💬
248 Pioglitazone [1] Pioglitazone[1] Pioglitazone 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
249 Piribedil [1] Piribedil[1] Piribedil 💬[2] DRD2,
DRD3 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
250 Pitolisant [1] Pitolisant[1] Pitolisant 💬[1] HRH3 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
251 Plantago seed [2] Psyllium; Psyllium husk[1] Plantago seed 💬--[3] 6, 28, 97 💬
252 Polyethylene glycol [4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350[1] Polyethylene glycol 3350 💬--[17] 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337 💬
253 Posiphen [1] Posiphen---[1] 6 💬
254 Potassium carbonate [0] [1] Potassium carbonate 💬--[3] 6, 96, 291 💬
255 Pramipexole [7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[1] Pramipexole 💬[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20 💬
256 Prasinezumab [1] Prasinezumab[1] Prasinezumab 💬[1] SNCA 💬[3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 6 💬
257 Preladenant [1] Preladenant[1] Preladenant 💬[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
258 Pridopidine [1] Pridopidine[1] Pridopidine 💬[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
259 Propanoic acid [1] Propanoic acid---[2] 6, 271 💬
260 Propofol [2] Propofol; Propofol Injection[1] Propofol 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
261 Propranolol [2] Propanolol; Propranolol[1] Propranolol 💬[3] ADRB1,
ADRB2,
ADRB3 💬		[12] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 158, 167, 227, 278, 296 💬
262 Psilocybin [2] Psilocybin; Psilocybine---[1] 6 💬
263 Pyridostigmine [3] Mestinon; PYRIDOSTIGMINE; PYRIDOSTIGMINE BROMIDE---[4] 3, 6, 11, 256 💬
264 Pyridoxine [2] Pyridoxine; Vitamin B6[1] Pyridoxine 💬--[5] 6, 93, 145, 206, 320 💬
265 Pyrimethamine [2] Daraprim; Pyrimethamine[1] Pyrimethamine 💬--[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬
266 Quetiapine [2] Quetiapine; Seroquel[1] Quetiapine 💬[2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
267 Quinine [0] [2] Quinine ,
Quinine dihydrochloride 💬		--[1] 6 💬
268 Raclopride [1] Raclopride---[4] 5, 6, 7, 17 💬
269 Radotinib [1] Radotinib---[1] 6 💬
270 Ramelteon [2] Ramelteon; ROZEREM[1] Ramelteon 💬[2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46 💬
271 Rasagiline [4] AZILECT; Rasagilina; RASAGILINE; RASAGILINE MESYLATE[2] Rasagiline ,
Rasagiline tartrate 💬		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[6] 2, 5, 6, 17, 58, 66 💬
272 Remifentanil [2] Remifentanil; Remifentanyl[1] Remifentanil 💬[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 6, 70 💬
273 Repaglinide [1] Repaglinide[1] Repaglinide 💬[2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
274 Reynoutria multiflora root [1] Heshouwu---[1] 6 💬
275 Rifampicin [2] RIFAMPICIN; Rifampin[1] Rifampin 💬--[9] 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
276 Rifaximin [3] Rifaximin; RIFAXIMINA; Xifaxan[1] Rifaximin 💬--[9] 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
277 Rivastigmine [3] EXELON; Rivastigmine; Rivastigmine Transdermal System[1] Rivastigmine 💬[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13 💬
278 Ropinirole [3] Requip; Ropinirole; ROPINIROLE HYDROCHLORIDE[1] Ropinirole 💬[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309 💬
279 Rosuvastatin [3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
280 Rotigotine [3] NEUPRO; ROTIGOTINA; ROTIGOTINE[1] Rotigotine 💬[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
281 Safinamide [3] Safinamida; SAFINAMIDE; Xadago[1] Safinamide 💬[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
282 Sage [1] Sage---[1] 6 💬
283 Saracatinib [1] Saracatinib[1] Saracatinib 💬[2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272 💬
284 Sarcosine [1] Sarcosine---[1] 6 💬
285 Sargramostim [2] Leukine; Sargramostim[1] Sargramostim 💬[1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
286 Sarizotan [1] SARIZOTAN---[2] 6, 156 💬
287 Selegiline [2] SELEGILINE; Zelapar[1] Selegiline 💬[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
288 Semaglutide [1] Semaglutide[1] Semaglutide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
289 SEP-363856 [1] SEP-363856---[1] 6 💬
290 Serine [2] L-Serine; Serine[1] Serine 💬--[4] 2, 6, 86, 96 💬
291 Sertraline [1] Sertraline[1] Sertraline 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206 💬
292 Sevoflurane [1] Sevoflurane[1] Sevoflurane 💬--[7] 6, 21, 22, 34, 98, 225, 296 💬
293 Sildenafil [6] Mysildecard; REVATIO; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; VIAGRA[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
294 Silodosin [2] Silodosin; Silodyx[1] Silodosin 💬[1] ADRA1A 💬[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13 💬
295 Simvastatin [3] Simvastatin; Simvastatina; Simvastatine[1] Simvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
296 Sitagliptin [1] Sitagliptin[1] Sitagliptin 💬[1] DPP4 💬[1] Protein digestion and absorption 💬[4] 6, 75, 233, 299 💬
297 Smilagenin [1] SMILAGENIN---[1] 6 💬
298 Sodium chloride [6] Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; Sporanox[1] Sodium chloride 💬--[20] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬
299 Sodium oxybate [1] Sodium Oxybate[1] Sodium oxybate 💬--[2] 6, 149 💬
300 Solifenacin [2] Solifenacin; Solifenacin Succinate[1] Solifenacin 💬[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
301 Spheramine [1] Spheramine---[1] 6 💬
302 ST-36 [0] ---[2] 6, 49 💬
303 Sulfachlorpyridazine [0] [1] Sulfachlorpyridazine 💬--[1] 6 💬
304 Sulfanilamide [0] [1] Sulfanilamide 💬--[4] 6, 30, 60, 298 💬
305 Sulfate ion [1] Sulfate---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
306 Sulforaphane [1] Sulforaphane---[2] 6, 205 💬
307 Sulpiride [0] [1] Sulpiride 💬[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 70 💬
308 Sumanirole [1] Sumanirole---[1] 6 💬
309 Suvorexant [1] Suvorexant[1] Suvorexant 💬[2] HCRTR1,
HCRTR2 💬		[1] Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬
310 Tacrolimus [2] Prograf; TACROLIMUS[2] Tacrolimus ,
Tacrolimus 💬		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
311 Tadalafil [4] Adcirca; CIALIS; TADALAFIL; TADALAFILO[1] Tadalafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210 💬
312 Talampanel [1] Talampanel[1] Talampanel 💬[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6 💬
313 Tavapadon [2] PF-06649751; TAVAPADON[1] Tavapadon 💬[2] DRD1,
DRD5 💬		[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6 💬
314 Technetium Tc-99m exametazime [1] Ceretec---[1] 6 💬
315 Terazosin [1] Terazosin[1] Terazosin 💬[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6 💬
316 Tesofensine [1] Tesofensine---[2] 6, 193 💬
317 Tolcapone [3] Tasmar; Tolcapon; Tolcapone[1] Tolcapone 💬[1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127 💬
318 Topiramate [2] TOPAMAX; Topiramate[1] Topiramate 💬[36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
319 Tozadenant [1] TOZADENANT[1] Tozadenant 💬[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
320 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113 💬
321 Tributyrin [1] Tributyrin---[1] 6 💬
322 Trihexyphenidyl [1] Trihexyphenidyl[1] Trihexyphenidyl 💬[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6 💬
323 Trimethobenzamide [3] Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride[1] Trimethobenzamide 💬--[1] 6 💬
324 Tropicamide [1] Tropicamide[1] Tropicamide 💬[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
325 Tryptophan [2] Propanoic acid; Tryptophan[1] Tryptophan 💬--[2] 6, 75 💬
326 Tulobuterol [1] Tulobuterol[1] Tulobuterol 💬[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
327 Tyrosine [4] Alanine; L-tyrosine; Propanoic acid; Tyrosine[1] Tyrosine 💬--[5] 6, 75, 86, 111, 298 💬
328 Ubidecarenone [3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] Ubidecarenone 💬--[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
329 Ubiquinol [1] Ubiquinol---[3] 6, 8, 17 💬
330 Uric acid [1] Urate---[1] 6 💬
331 Ursodeoxycholic acid [4] UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk[1] Ursodiol 💬[1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
332 Valerian [1] Valerian---[1] 6 💬
333 Valiloxybate [1] Valiloxybate[1] Valiloxybate 💬[2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
334 Valproic acid [3] Valproate; VALPROATE SODIUM; Valproic acid[1] Valproic acid 💬[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
335 Varenicline [2] Champix; Varenicline[1] Varenicline 💬[2] CHRNA4,
CHRNB2 💬		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53 💬
336 Venglustat [2] GENZ-682452; Venglustat[1] Venglustat 💬[1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
337 Venlafaxine [2] Venlafaxine; Venlafaxine Hydrochloride[1] Venlafaxine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46 💬
338 Vitamin E [2] Alpha-tocopherol; Vitamin E[1] Vitamin E 💬--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
339 Vortioxetine [1] Vortioxetine[1] Vortioxetine 💬[7] HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬		[5] Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
340 Warfarin [2] Warfarin; Warfarin Sodium[1] Warfarin 💬[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
341 Water [8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] Water 💬--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
342 Wheat [1] Wheat[1] Wheat 💬--[2] 6, 53 💬
343 Wheat bran [1] Wheat bran---[1] 6 💬
344 Yohimbine [1] Yohimbine[1] Yohimbine 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 6 💬
345 Zoledronic acid [4] ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa[2] Zoledronic acid ,
Zoledronic acid 💬		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
346 Zolmitriptan [1] Zolmitriptan[1] Zolmitriptan 💬[2] HTR1B,
HTR1D 💬		[4] Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
347 Zolpidem [2] Zolpidem; Zolpidem Tartrate[1] Zolpidem 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬
348 Zonisamide [2] Zonegran; Zonisamide[1] Zonisamide 💬[8] CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[11] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬[1] 6 💬
349 Zopiclone [1] Zopiclone[1] Zopiclone 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬