Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Indomethacin 💬 1件: Indomethacin2件: INDOMETACIN; Indomethacin; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
2 Acetazolamide 💬 1件: Acetazolamide1件: Acetazolamide; 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬6件: 13, 90, 115, 155, 225, 230 💬
3 Desmopressin 💬 1件: Desmopressin5件: DDAVP; Desmopressin; Desmopressin Acetate; Desmopressine; Minirin; 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288 💬
4 Fluconazole 💬 1件: Fluconazole2件: Diflucan; FLUCONAZOLE; --2件: 96, 225 💬
5 Hydrochlorothiazide 💬 1件: Hydrochlorothiazide2件: Esidrix; Hydrochlorothiazide; 1件: SLC12A3 💬1件: 💬4件: 13, 67, 225, 235 💬
6 Spironolactone 💬 1件: Spironolactone1件: Spironolactone; 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225 💬
7 Omeprazole 💬 1件: Omeprazole4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
8 Chlorothiazide 💬 1件: Chlorothiazide1件: Chlorothiazide; 1件: SLC12A3 💬1件: 💬1件: 225 💬
9 Sevoflurane 💬 1件: Sevoflurane1件: Sevoflurane; --7件: 6, 21, 22, 34, 98, 225, 296 💬
10 Tolvaptan 💬 1件: Tolvaptan3件: Jinarc; Samsca; TOLVAPTAN; 1件: AVPR2 💬3件: Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 67, 72, 86, 225 💬
11 Metformin 💬 1件: Metformin5件: Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine; 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
12 Amiloride 💬 1件: Amiloride3件: Amiloride; Amiloride Hydrochloride; Midamor; 3件: SCNN1A,
SCNN1B,
SCNN1G 💬		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299 💬
13 Atorvastatin 💬 1件: Atorvastatin3件: Atorvastatin; Atorvastatin calcium; Lipitor; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
14 Sildenafil 💬 1件: Sildenafil6件: Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra; 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
15 Riociguat 💬 1件: Riociguat2件: ADEMPAS; RIOCIGUAT; 3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬6件: 51, 84, 86, 88, 225, 299 💬