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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1(7R,8R,9R)-2.3-Dimethyl-8-hydroxy-7(2-methoxyethoxy)- 9-phenyl-7.8.9.10-tetrahydro-imidazo-[1.2-h].[1.7].- naphthyridine----1件: 301
24-Methylpyrazole1件: Fomepizole1件: D00707 3件: ADH1A,
ADH1B,
ADH1C 💬
9件: Alcoholic liver disease, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism 💬1件: 301
3[ACU-4429]1件: Emixustat1件: D10348 --1件: 301
4[ARC1905]1件: Avacincaptad pegol---1件: 301
5[EU/3/13/1208 orphan]----1件: 301
6ACU-44291件: Emixustat1件: D10348 --1件: 301
7ALK-001----1件: 301
8ALK-001 (No generic name)----1件: 301
9ARC19051件: Avacincaptad pegol---1件: 301
10ARC1905 20 MG/ML1件: Avacincaptad pegol---1件: 301
11Avacincaptad pegol1件: Avacincaptad pegol---1件: 301
12DHA1件: Doconexent---8件: 6, 46, 48, 49, 94, 113, 299, 301
13Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
14Docosahexaenoic acid1件: Doconexent---7件: 6, 49, 90, 94, 240, 299, 301
15Docosahexaenoic Acid (DHA) Dietary Supplement1件: Doconexent---1件: 301
16Emixustat1件: Emixustat1件: D10348 --1件: 301
17Emixustat hydrochloride1件: Emixustat1件: D10348 --1件: 301
18EMIXUSTAT HYDROCHLORIDE (ACU-4429)1件: Emixustat1件: D10348 --1件: 301
19EPA1件: Icosapent1件: D08061 --6件: 8, 46, 48, 49, 113, 301
20HESC-RPE----1件: 301
21Interferon Gamma1件: Interferon Gamma---8件: 18, 65, 85, 107, 228, 299, 301, 326
22INTERFERON GAMMA-1B1件: Interferon gamma-1b1件: D00747 2件: IFNGR1,
IFNGR2 💬
18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326
23Lentiviral vector containing ABCA4 gene----1件: 301
24Long term follow up in all patients who received SAR422459 in previous study TDU13583----1件: 301
25MA09-hRPE----1件: 301
26Madeos----1件: 301
27Metformin1件: Metformin2件: D00944 ,
D04966
2件: PRKAA1,
PRKAA2 💬
20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
28METFORMIN HYDROCHLORIDE1件: Metformin2件: D00944 ,
D04966
2件: PRKAA1,
PRKAA2 💬
20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬5件: 81, 158, 265, 299, 301
29Other: Saline----8件: 2, 6, 46, 97, 98, 256, 274, 301
30Other: Sham----1件: 301
31Other: Standard of Care Sildenafil1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
32Other: Visual Acuity (VA)1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
33Over the counter DHA/EPA dietary supplementation1件: Icosapent1件: D08061 --1件: 301
34Ranibizumab1件: Ranibizumab1件: D05697 1件: VEGFA 💬24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬4件: 34, 166, 227, 301
35Ranibizumab injection (0.5 mg)1件: Ranibizumab1件: D05697 1件: VEGFA 💬24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 166, 301
36Saffron supplementation----1件: 301
37SAR422459----1件: 301
38Sildenafil1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
39SORAPRAZAN----1件: 301
40StarGen----1件: 301
41Stem/progenitor cells transplantation----2件: 90, 301
42STG-0011件: STG-001---1件: 301
43Tinlarebant----1件: 301
44VA1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬3件: 90, 301, 302
45Vett Lentiviral con gene ABCA4----1件: 301
46Zimura1件: Avacincaptad pegol---1件: 301