Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Butalbital and Acetaminophen 50 mg/325 mg)		4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: Acetaminophen 💬2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Amiloride
(Nu-amilzide 5/50 Mg Tab)		3件: AMILORIDE; Amiloride Hydrochloride; Midamor1件: Amiloride 💬3件: SCNN1A,
SCNN1B,
SCNN1G 💬		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299 💬
3 Amphotericin B
(Amphotec 50 mg)		2件: ABELCET; Amphotericin B1件: Amphotericin B 💬--1件: 299 💬
4 Atenolol
(Riva-atenolol 50 mg)		1件: ATENOLOL1件: Atenolol 💬1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167 💬
5 Azathioprine
(Riva-azathioprine 50 mg)		3件: Azathioprine; Azatioprina; Imuran1件: Azathioprine 💬--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
6 Celecoxib
(Celecoxib 50 mg)		2件: Celebrex; Celecoxib1件: Celecoxib 💬1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
7 Diclofenac
(Apo-diclo Rapide 50 Mg Tablets)		3件: Diclofenac; Diclofenac sodium; Diclofenac SR1件: Diclofenac 💬2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271 💬
8 Diphenhydramine
(Diphenhydramine Hydrochloride 50 Mg Caplet)		2件: Diphenhydramine; Diphenhydramine hydrochloride1件: Diphenhydramine 💬1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256 💬
9 Flurbiprofen
(Ansaid Tablets 50 mg)		1件: Flurbiprofen1件: Flurbiprofen 💬2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46 💬
10 Hydralazine
(Nu-hydral Tab 50 mg)		1件: Hydralazine1件: Hydralazine 💬1件: AOC3 💬5件: Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬1件: 67 💬
11 Hydrochlorothiazide
(Riva-amilzide 5/50 mg)		2件: Esidrix; HYDROCHLOROTHIAZIDE1件: Hydrochlorothiazide 💬1件: SLC12A3 💬-4件: 13, 67, 225, 235 💬
12 Losartan
(LOSARTAN POTASSIUM 50 mg)		3件: Cozaar; Losartan; LOSARTAN POTASSIUM1件: Losartan 💬1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13 Metoprolol
(Metoprolol Tartrate and Hydrochlorothiazide 50 mg-25 mg)		2件: Metoprolol; METOPROLOL SUCCINATE1件: Metoprolol 💬1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226 💬
14 Minocycline
(Riva-minocycline 50 mg)		3件: Minocycline; Minocycline Hydrochloride; Minomycin1件: Minocycline 💬--14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
15 Pyridoxine
(Vitamin B-6 50 Mg Tablet)		2件: PYRIDOXINE; Vitamin B61件: Pyridoxine 💬--5件: 6, 93, 145, 206, 320 💬
16 Riboflavin
(Vitamin B-2 50 Mg Tablets)		2件: Riboflavin; Vitamin B21件: Riboflavin 💬--7件: 38, 46, 96, 97, 162, 168, 265 💬
17 Ubidecarenone
(Coenzyme Q10 50 mg)		3件: Coenzyme Q-10; Coenzyme Q10; CoQ101件: Ubidecarenone 💬--12件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
18 Zinc gluconate
(Zinc 50 Mg - Tab)		1件: ZINC GLUCONATE1件: Zinc gluconate 💬--1件: 171 💬