Drug Description in Trials / DrugBank / KEGG DRUG


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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Azathioprine
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
2Azathioprine (AZA)
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--3件: 13, 19, 97 💬
3Azathioprine (AZA) caps
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 96 💬
4Azathioprine (AZA) or 6-mercaptopurine (6-MP)
(D00238)
2件: Azathioprine,
Mercaptopurine
3件: Mercaptopurine ,
Azathioprine (D00238),
Mercaptopurine 💬
1件: HPRT1 💬4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬2件: 96, 97 💬
5Azathioprine (Imuran) 50 mg Overencapsulated Tablet
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 97 💬
6Azathioprine + infliximab
(D00238)
2件: Azathioprine,
Infliximab
2件: Azathioprine (D00238),
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
7Azathioprine - ratiopharm 50 mg
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 96 💬
8Azathioprine / 6 Mercaptopurine
(D00238)
2件: Azathioprine,
Mercaptopurine
3件: Mercaptopurine ,
Azathioprine (D00238),
Mercaptopurine 💬
1件: HPRT1 💬4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬1件: 96 💬
9Azathioprine 25 mg
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 44 💬
10Azathioprine and Allopurinol
(D00238)
2件: Allopurinol,
Azathioprine
2件: Allopurinol ,
Azathioprine (D00238) 💬
1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬1件: 97 💬
11AZATHIOPRINE BP
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 97 💬
12Azathioprine in case of endoscopic recurrence
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 96 💬
13Azathioprine individualised dose
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 96 💬
14Azathioprine or 6-mercaptopurine
(D00238)
2件: Azathioprine,
Mercaptopurine
3件: Mercaptopurine ,
Azathioprine (D00238),
Mercaptopurine 💬
1件: HPRT1 💬4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬2件: 96, 97 💬
15Azathioprine or adalimumab and infliximab
(D00238)
3件: Adalimumab,
Azathioprine,
Infliximab
3件: Azathioprine (D00238),
Adalimumab ,
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
16Azathioprine OR Mesalazine
(D00238)
2件: Azathioprine,
Mesalazine
2件: Azathioprine (D00238),
Mesalamine 💬
--1件: 96 💬
17AZATHIOPRINE or METHOTREXATE
(D00238)
2件: Azathioprine,
Methotrexate
2件: Methotrexate ,
Azathioprine (D00238) 💬
2件: DHFR,
DHFR2 💬
5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬1件: 96 💬
18Azathioprine or Mycophenolate mofetil
(D00238)
3件: Azathioprine,
Mycophenolate mofetil,
Mycophenolic acid
3件: Azathioprine (D00238),
Mycophenolate mofetil ,
Mycophenolic acid 💬
2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬1件: 162 💬
19Azathioprine weight-based dose
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 96 💬
20Azathioprine+enteral nutrition
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 96 💬
21Azathioprine/prednisone
(D00238)
2件: Azathioprine,
Prednisone
2件: Azathioprine (D00238),
Prednisone 💬
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 85 💬
22Combination of Protein A Immunoadsorption, Rituximab, Dexamethasone plus Azathioprine
(D00238)
3件: Azathioprine,
Dexamethasone,
Rituximab
3件: Azathioprine (D00238),
Dexamethasone ,
Rituximab 💬
2件: MS4A1,
NR3C1 💬
2件: Hematopoietic cell lineage, Neuroactive ligand-receptor interaction 💬1件: 35 💬
23Continuation of azathioprine
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 49 💬
24Corticosteroid and azathioprine
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--4件: 42, 43, 44, 45 💬
25Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids
(D00238)
3件: Azathioprine,
Cyclophosphamide,
Methotrexate
4件: Methotrexate ,
Azathioprine (D00238),
Cyclophosphamide ,
Cyclophosphamide 💬
2件: DHFR,
DHFR2 💬
5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬1件: 44 💬
26Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
(D00238)
4件: Azathioprine,
Cyclophosphamide,
Methylprednisolone,
Prednisone
5件: Azathioprine (D00238),
Cyclophosphamide ,
Methylprednisolone ,
Prednisone ,
Cyclophosphamide 💬
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 42, 43, 45 💬
27Cyclophosphamide-prednisone-azathioprine
(D00238)
3件: Azathioprine,
Cyclophosphamide,
Prednisone
4件: Azathioprine (D00238),
Cyclophosphamide ,
Prednisone ,
Cyclophosphamide 💬
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 49 💬
28Early immunosuppressants (azathioprine, methotrexate)
(D00238)
2件: Azathioprine,
Methotrexate
2件: Methotrexate ,
Azathioprine (D00238) 💬
2件: DHFR,
DHFR2 💬
5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬1件: 96 💬
29Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)
(D00238)
4件: Azathioprine,
Methotrexate,
Mycophenolate mofetil,
Mycophenolic acid
4件: Methotrexate ,
Azathioprine (D00238),
Mycophenolate mofetil ,
Mycophenolic acid 💬
4件: DHFR,
DHFR2,
IMPDH1,
IMPDH2 💬
8件: Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, Nucleotide metabolism, One carbon pool by folate, Purine metabolism 💬1件: 49 💬
30Infliximab and azathioprine combination at week 0
(D00238)
2件: Azathioprine,
Infliximab
2件: Azathioprine (D00238),
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
31Infliximab and azathioprine combination at week 14
(D00238)
2件: Azathioprine,
Infliximab
2件: Azathioprine (D00238),
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
32Infliximab with azathioprine (IIFX + AZA)
(D00238)
2件: Azathioprine,
Infliximab
2件: Azathioprine (D00238),
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
33Infliximab+azathioprine
(D00238)
2件: Azathioprine,
Infliximab
2件: Azathioprine (D00238),
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
34Infliximab, azathioprine
(D00238)
2件: Azathioprine,
Infliximab
2件: Azathioprine (D00238),
Infliximab 💬
1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 96 💬
35Methylprednisolone and azathioprine
(D00238)
2件: Azathioprine,
Methylprednisolone
2件: Azathioprine (D00238),
Methylprednisolone 💬
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 93, 95 💬
36Overencapsulated Azathioprine (Imuran) 50 mg Tablet
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 97 💬
37Prednisone - Azathioprine
(D00238)
2件: Azathioprine,
Prednisone
2件: Azathioprine (D00238),
Prednisone 💬
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 11 💬
38Products containing azathioprine or 6-mercaptopurine
(D00238)
2件: Azathioprine,
Mercaptopurine
3件: Mercaptopurine ,
Azathioprine (D00238),
Mercaptopurine 💬
1件: HPRT1 💬4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬1件: 97 💬
39Rituximab (RTX) and Azathioprine (AZA)
(D00238)
2件: Azathioprine,
Rituximab
2件: Azathioprine (D00238),
Rituximab 💬
1件: MS4A1 💬1件: Hematopoietic cell lineage 💬1件: 65 💬
40Steroids plus azathioprine
(D00238)
1件: Azathioprine1件: Azathioprine (D00238) 💬--1件: 66 💬