Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 TUBB3 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D11595 Belantamab mafodotin 1件: 28
2 TUBB4A 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D11595 Belantamab mafodotin 1件: 28
3 TUBB4B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D11595 Belantamab mafodotin 1件: 28
4 COMT 4件: Steroid hormone biosynthesis 💬, Tyrosine metabolism 💬, Metabolic pathways 💬, Dopaminergic synapse 💬 D00786 Tolcapone 3件: 6, 28, 127
5 CSF1 12件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, PI3K-Akt signaling pathway 💬, Osteoclast differentiation 💬, Hematopoietic cell lineage 💬, TNF signaling pathway 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Rheumatoid arthritis 💬 D06402 Sunitinib 2件: 28, 34
6 CSF1 12件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, PI3K-Akt signaling pathway 💬, Osteoclast differentiation 💬, Hematopoietic cell lineage 💬, TNF signaling pathway 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Rheumatoid arthritis 💬 D08552 Sunitinib 2件: 28, 34
7 CSF2RA 4件: Cytokine-cytokine receptor interaction 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D05803 Sargramostim 7件: 6, 28, 60, 62, 96, 229, 285
8 CSF3R 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D03235 Filgrastim 34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
9 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D00636 Amiodarone 2件: 28, 127
10 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D02910 Amiodarone 2件: 28, 127
11 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D00636 Amiodarone 2件: 28, 127
12 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D02910 Amiodarone 2件: 28, 127
13 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D00636 Amiodarone 2件: 28, 127
14 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D02910 Amiodarone 2件: 28, 127
15 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D00636 Amiodarone 2件: 28, 127
16 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D02910 Amiodarone 2件: 28, 127
17 TUBB 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D11595 Belantamab mafodotin 1件: 28
18 FLT1 9件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, HIF-1 signaling pathway 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Transcriptional misregulation in cancer 💬, Rheumatoid arthritis 💬 D06402 Sunitinib 2件: 28, 34
19 FLT1 9件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, HIF-1 signaling pathway 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Transcriptional misregulation in cancer 💬, Rheumatoid arthritis 💬 D08552 Sunitinib 2件: 28, 34
20 FLT3 8件: MAPK signaling pathway 💬, Ras signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Acute myeloid leukemia 💬, Central carbon metabolism in cancer 💬 D06402 Sunitinib 2件: 28, 34
21 FLT3 8件: MAPK signaling pathway 💬, Ras signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Acute myeloid leukemia 💬, Central carbon metabolism in cancer 💬 D08552 Sunitinib 2件: 28, 34
22 FLT4 8件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Pathways in cancer 💬, Breast cancer 💬 D06402 Sunitinib 2件: 28, 34
23 FLT4 8件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Pathways in cancer 💬, Breast cancer 💬 D08552 Sunitinib 2件: 28, 34
24 ABL1 11件: ErbB signaling pathway 💬, Ras signaling pathway 💬, Cell cycle 💬, Axon guidance 💬, Neurotrophin signaling pathway 💬, Pathogenic Escherichia coli infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - reactive oxygen species 💬, Chronic myeloid leukemia 💬, Viral myocarditis 💬 D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
25 ABL1 11件: ErbB signaling pathway 💬, Ras signaling pathway 💬, Cell cycle 💬, Axon guidance 💬, Neurotrophin signaling pathway 💬, Pathogenic Escherichia coli infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - reactive oxygen species 💬, Chronic myeloid leukemia 💬, Viral myocarditis 💬 D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
26 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00244 Betamethasone 6件: 28, 46, 83, 90, 96, 235
27 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00292 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
28 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00972 Betamethasone 6件: 28, 46, 83, 90, 96, 235
29 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00975 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
30 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01357 Betamethasone 6件: 28, 46, 83, 90, 96, 235
31 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01402 Betamethasone 6件: 28, 46, 83, 90, 96, 235
32 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01510 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
33 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01615 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
34 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01632 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
35 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01637 Betamethasone 6件: 28, 46, 83, 90, 96, 235
36 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01948 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
37 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02032 Betamethasone 6件: 28, 46, 83, 90, 96, 235
38 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02174 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
39 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02286 Betamethasone 6件: 28, 46, 83, 90, 96, 235
40 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02591 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
41 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02592 Dexamethasone 22件: 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
42 HRH1 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Inflammatory mediator regulation of TRP channels 💬 D00664 Cetirizine 4件: 13, 28, 35, 300
43 HRH1 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Inflammatory mediator regulation of TRP channels 💬 D07662 Cetirizine 4件: 13, 28, 35, 300
44 IFNAR1 18件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Influenza A 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬 D03305 Interferon alfa 6件: 13, 25, 26, 28, 56, 96
45 IFNAR2 17件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Hepatitis C 💬, Measles 💬, Influenza A 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬 D03305 Interferon alfa 6件: 13, 25, 26, 28, 56, 96
46 TUBB8 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D11595 Belantamab mafodotin 1件: 28
47 TUBB2B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D11595 Belantamab mafodotin 1件: 28
48 IL1R1 13件: MAPK signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Inflammatory mediator regulation of TRP channels 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Amoebiasis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Fluid shear stress and atherosclerosis 💬 D02934 Anakinra 19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
49 IL6 51件: EGFR tyrosine kinase inhibitor resistance 💬, Antifolate resistance 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, PI3K-Akt signaling pathway 💬, Cellular senescence 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, Cytosolic DNA-sensing pathway 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, TNF signaling pathway 💬, Intestinal immune network for IgA production 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Alcoholic liver disease 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬, Pertussis 💬, Legionellosis 💬, Yersinia infection 💬, Chagas disease 💬, African trypanosomiasis 💬, Malaria 💬, Amoebiasis 💬, Tuberculosis 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬, Graft-versus-host disease 💬, Hypertrophic cardiomyopathy 💬, Lipid and atherosclerosis 💬 D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
50 IL6 51件: EGFR tyrosine kinase inhibitor resistance 💬, Antifolate resistance 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, PI3K-Akt signaling pathway 💬, Cellular senescence 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, Cytosolic DNA-sensing pathway 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, TNF signaling pathway 💬, Intestinal immune network for IgA production 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Alcoholic liver disease 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬, Pertussis 💬, Legionellosis 💬, Yersinia infection 💬, Chagas disease 💬, African trypanosomiasis 💬, Malaria 💬, Amoebiasis 💬, Tuberculosis 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬, Graft-versus-host disease 💬, Hypertrophic cardiomyopathy 💬, Lipid and atherosclerosis 💬 D09669 Siltuximab 2件: 28, 331
51 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00752 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
52 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05094 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
53 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05095 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
54 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05096 Mycophenolic acid 36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
55 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00752 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
56 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05094 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
57 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05095 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
58 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05096 Mycophenolic acid 36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
59 KCND3 1件: Spinocerebellar ataxia 💬 D00636 Amiodarone 2件: 28, 127
60 KCND3 1件: Spinocerebellar ataxia 💬 D02910 Amiodarone 2件: 28, 127
61 KCNJ3 10件: Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Cholinergic synapse 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Estrogen signaling pathway 💬, Oxytocin signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D00636 Amiodarone 2件: 28, 127
62 KCNJ3 10件: Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Cholinergic synapse 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Estrogen signaling pathway 💬, Oxytocin signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D02910 Amiodarone 2件: 28, 127
63 KCNJ5 9件: Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Estrogen signaling pathway 💬, Oxytocin signaling pathway 💬, Aldosterone synthesis and secretion 💬, GnRH secretion 💬, Morphine addiction 💬 D00636 Amiodarone 2件: 28, 127
64 KCNJ5 9件: Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Estrogen signaling pathway 💬, Oxytocin signaling pathway 💬, Aldosterone synthesis and secretion 💬, GnRH secretion 💬, Morphine addiction 💬 D02910 Amiodarone 2件: 28, 127
65 KCNJ8 1件: cGMP-PKG signaling pathway 💬 D00636 Amiodarone 2件: 28, 127
66 KCNJ8 1件: cGMP-PKG signaling pathway 💬 D02910 Amiodarone 2件: 28, 127
67 KCNJ11 3件: Insulin secretion 💬, GnRH secretion 💬, Type II diabetes mellitus 💬 D00636 Amiodarone 2件: 28, 127
68 KCNJ11 3件: Insulin secretion 💬, GnRH secretion 💬, Type II diabetes mellitus 💬 D02910 Amiodarone 2件: 28, 127
69 KCNJ12 2件: Cholinergic synapse 💬, Oxytocin signaling pathway 💬 D00636 Amiodarone 2件: 28, 127
70 KCNJ12 2件: Cholinergic synapse 💬, Oxytocin signaling pathway 💬 D02910 Amiodarone 2件: 28, 127
71 KCNQ1 6件: Adrenergic signaling in cardiomyocytes 💬, Cholinergic synapse 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Protein digestion and absorption 💬, Vibrio cholerae infection 💬 D00636 Amiodarone 2件: 28, 127
72 KCNQ1 6件: Adrenergic signaling in cardiomyocytes 💬, Cholinergic synapse 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Protein digestion and absorption 💬, Vibrio cholerae infection 💬 D02910 Amiodarone 2件: 28, 127
73 KDR 10件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, PI3K-Akt signaling pathway 💬, VEGF signaling pathway 💬, Focal adhesion 💬, Proteoglycans in cancer 💬, Fluid shear stress and atherosclerosis 💬 D06402 Sunitinib 2件: 28, 34
74 KDR 10件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, PI3K-Akt signaling pathway 💬, VEGF signaling pathway 💬, Focal adhesion 💬, Proteoglycans in cancer 💬, Fluid shear stress and atherosclerosis 💬 D08552 Sunitinib 2件: 28, 34
75 KIT 11件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Melanogenesis 💬, Pathways in cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Central carbon metabolism in cancer 💬 D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
76 KIT 11件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Melanogenesis 💬, Pathways in cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Central carbon metabolism in cancer 💬 D06402 Sunitinib 2件: 28, 34
77 KIT 11件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Melanogenesis 💬, Pathways in cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Central carbon metabolism in cancer 💬 D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
78 KIT 11件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Melanogenesis 💬, Pathways in cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Central carbon metabolism in cancer 💬 D08552 Sunitinib 2件: 28, 34
79 LTA 7件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, NF-kappa B signaling pathway 💬, TNF signaling pathway 💬, Type I diabetes mellitus 💬, Human T-cell leukemia virus 1 infection 💬, Herpes simplex virus 1 infection 💬 D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
80 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
81 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D06402 Sunitinib 2件: 28, 34
82 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
83 PDGFRA 20件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D08552 Sunitinib 2件: 28, 34
84 PDGFRB 19件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human papillomavirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D06402 Sunitinib 2件: 28, 34
85 PDGFRB 19件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Focal adhesion 💬, Gap junction 💬, JAK-STAT signaling pathway 💬, Regulation of actin cytoskeleton 💬, Human papillomavirus infection 💬, Pathways in cancer 💬, MicroRNAs in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬 D08552 Sunitinib 2件: 28, 34
86 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
87 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
88 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
89 PPP3R1 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
90 PPP3R2 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬,