Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Cholecalciferol 💬 1件: Cholecalciferol5件: CHOLECALCIFEROL; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬16件: 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
2 Budesonide 💬 1件: Budesonide4件: Budesonide; Entocort; Jorveza; Symbicort; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
3 Famotidine 💬 1件: Famotidine2件: FAMOTIDINA; Famotidine; 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107 💬
4 Lansoprazole 💬 1件: Lansoprazole1件: Lansoprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299 💬
5 Loratadine 💬 1件: Loratadine2件: Loratadina; Loratadine; 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98 💬
6 Mesalamine 💬 1件: Mesalazine10件: 5-AminoSalicylic Acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; MESALAZINE; Mesalazinum; MEZAVANT; Pentasa; Salofalk; --5件: 46, 96, 97, 98, 164 💬
7 Sucralfate 💬 1件: Sucralfate1件: Sucralfate; --1件: 98 💬
8 Sevoflurane 💬 1件: Sevoflurane1件: Sevoflurane; --7件: 6, 21, 22, 34, 98, 225, 296 💬
9 Propofol 💬 1件: Propofol2件: Propofol; Propofol Injection; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬8件: 6, 21, 22, 34, 46, 70, 98, 296 💬
10 Beclomethasone dipropionate 💬 1件: Beclomethasone dipropionate2件: Beclometasone dipropionate; Beclomethasone dipropionate; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 85, 97, 98 💬
11 Mometasone furoate 💬 1件: Mometasone furoate3件: Mometasone; MOMETASONE FUROATE; Nasonex; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162 💬
12 Sirolimus 💬 1件: Sirolimus3件: Rapamune; Rapamycin; Sirolimus; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
13 Fluticasone propionate 💬 1件: Fluticasone propionate3件: Flovent; Fluticasone; Fluticasone propionate; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228 💬
14 Infliximab 💬 1件: Infliximab6件: Flixabi; Inflectra; Infliximab; Remicade; REMSIMA; Zessly; 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
15 Arginine 💬 2件: Arginine,
L-arginine		6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; --12件: 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299 💬
16 Mepolizumab 💬 1件: Mepolizumab2件: Mepolizumab; NUCALA; 1件: IL5 💬13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬4件: 44, 45, 98, 162 💬
17 Omalizumab 💬 1件: Omalizumab2件: Omalizumab; Xolair; 1件: FCER1A 💬4件: Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬7件: 46, 53, 65, 98, 162, 226, 299 💬
18 Citalopram 💬 1件: Citalopram1件: Citalopram; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127 💬
19 Cromoglicic acid 💬 1件: Cromoglicic acid4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium; --3件: 2, 85, 98 💬
20 Esomeprazole 💬 1件: Esomeprazole3件: Esomeprazole; Nexium; Omeprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
21 Fluticasone 💬 1件: Fluticasone1件: Fluticasone; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 98, 228, 299 💬
22 Losartan 💬 1件: Losartan3件: Cozaar; Losartan; LOSARTAN POTASSIUM; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
23 Mometasone 💬 1件: Mometasone1件: Mometasone; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162 💬
24 Montelukast 💬 1件: Montelukast3件: MONTELUKAST; MONTELUKAST SODIUM; Singulair; 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228 💬
25 Potassium 💬 1件: Potassium1件: Potassium; --13件: 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
26 Dexlansoprazole 💬 1件: Dexlansoprazole1件: Dexlansoprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬1件: 98 💬
27 Reslizumab 💬 1件: Reslizumab1件: Reslizumab; 1件: IL5 💬13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 98 💬
28 Benralizumab 💬 1件: Benralizumab2件: Benralizumab; Fasenra; 1件: IL5RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬5件: 44, 45, 98, 162, 299 💬
29 Dupilumab 💬 1件: Dupilumab2件: Dupilumab; Dupixent; 1件: IL4R 💬8件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬5件: 51, 97, 98, 160, 162 💬
30 Etrasimod 💬 1件: Etrasimod1件: Etrasimod; 5件: S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 96, 97, 98 💬
31 Tezepelumab 💬 1件: Tezepelumab3件: AMG 157; MEDI9929; Tezepelumab; 1件: TSLP 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98 💬
32 Vonoprazan 💬 1件: Vonoprazan1件: Vonoprazan; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 63, 98 💬
33 Lirentelimab 💬 1件: Lirentelimab1件: Lirentelimab; 1件: SIGLEC8 💬1件: 💬1件: 98 💬