Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Nra-tramadol/acet)		4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: Acetaminophen 💬2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Acetylsalicylic acid
(Nra-asa 80 Mg Croquable)		2件: Acetylsalicylic Acid; Aspirin1件: Aspirin 💬2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
3 Alendronic acid
(Nra-alendronate)		3件: Alendronate; Alendronate sodium; Alendronic acid1件: Alendronic acid 💬1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299 💬
4 Amlodipine
(Nra-amlodipine)		1件: AMLODIPINE1件: Amlodipine 💬4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298 💬
5 Apixaban
(Nra-apixaban)		2件: Apixaban; Eliquis1件: Apixaban 💬1件: F10 💬1件: Complement and coagulation cascades 💬1件: 222 💬
6 Atorvastatin
(Nra-atorvastatin)		3件: Atorvastatin; Atorvastatin Calcium; Lipitor1件: Atorvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
7 Azithromycin
(Nra-azithromycin)		5件: AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax2件: Azithromycin ,
Azithromycin 💬		--6件: 13, 84, 85, 96, 228, 299 💬
8 Biotin
(Nrg Plus Liq)		4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: Biotin 💬--5件: 2, 8, 10, 13, 20 💬
9 Candesartan cilexetil
(Nra-candesartan)		1件: CANDESARTAN1件: Candesartan cilexetil 💬1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 67 💬
10 Celecoxib
(Nra-celecoxib)		2件: Celebrex; Celecoxib1件: Celecoxib 💬1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
11 Cetirizine
(Nra-cetirizine Tablets)		3件: Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE1件: Cetirizine 💬1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300 💬
12 Chlorpheniramine
(Dometuss-NR)		1件: Clorfenamina1件: Chlorphenamine 💬1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14 💬
13 Cholecalciferol
(Nrg Plus Liq)		5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: Cholecalciferol 💬1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
14 Choline
(Nrg Plus Liq)		1件: Choline1件: Choline 💬--4件: 93, 171, 193, 299 💬
15 Ciprofloxacin
(Nra-ciprofloxacin)		2件: Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE1件: Ciprofloxacin 💬--5件: 2, 60, 96, 97, 299 💬
16 Citalopram
(Nra-citalopram)		1件: Citalopram1件: Citalopram 💬1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127 💬
17 Clindamycin
(Nra-clindamycin)		2件: Clindamycin; Dalacin C phosphate1件: Clindamycin 💬--2件: 46, 299 💬
18 Clopidogrel
(Nra-clopidogrel)		1件: Clopidogrel3件: Clopidogrel ,
Clopidogrel hydrochloride ,
Clopidogrel besilate 💬		1件: P2RY12 💬1件: Platelet activation 💬3件: 49, 51, 86 💬
19 Cyanocobalamin
(Nrg Plus Liq)		2件: Cianocobalamina; Vitamin B124件: Cyanocobalamin ,
Cyanocobalamin Co 57 ,
Cyanocobalamin Co 58 ,
Cyanocobalamin Co 60 💬		--5件: 6, 13, 201, 229, 299 💬
20 Dextromethorphan
(Brontuss SF-NR)		4件: Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta1件: Dextromethorphan 💬6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
21 Diazepam
(NRL-1)		1件: Diazepam1件: Diazepam 💬16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 46, 155, 298 💬
22 Duloxetine
(Nra-duloxetine)		3件: CYMBALTA; Duloxetine; Duloxetine hydrochloride1件: Duloxetine 💬2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13 💬
23 Escitalopram
(Nra-escitalopram)		3件: Citalopram; Escitalopram; Escitalopram oxalate1件: Escitalopram 💬1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46 💬
24 Ethanol
(Nrl Pure Daily Hand Sanitizer)		3件: Alcohol; Ethanol; PREDNISONE1件: Ethanol 💬--5件: 58, 97, 279, 280, 298 💬
25 Ezetimibe
(Nra-ezetimibe)		2件: EZETIMIBE; Ezetrol1件: Ezetimibe 💬1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260 💬
26 Flecainide
(Nra-flecainide)		3件: Flecainide; FLECAINIDE ACETATE; Flecainidum1件: Flecainide 💬5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6 💬
27 Fluoxetine
(Nra-fluoxetine)		5件: Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC1件: Fluoxetine 💬1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206 💬
28 Hydrochlorothiazide
(Nra-olmesartan Hctz)		2件: Esidrix; Hydrochlorothiazide1件: Hydrochlorothiazide 💬1件: SLC12A3 💬-4件: 13, 67, 225, 235 💬
29 Hydroxychloroquine
(Nra-hydroxychloroquine)		3件: Hydroxychloroquine; Hydroxychloroquine Sulfate; Plaquenil1件: Hydroxychloroquine 💬--27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
30 Inositol
(Nrg Plus Liq)		1件: Inositol1件: Inositol 💬--2件: 96, 97 💬
31 Lacosamide
(Nra-lacosamide)		1件: Lacosamide1件: Lacosamide 💬2件: SCN3A,
SCN9A 💬		1件: Taste transduction 💬4件: 2, 46, 149, 298 💬
32 Letrozole
(Nra-letrozole)		1件: Letrozole1件: Letrozole 💬1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬2件: 81, 89 💬
33 Levetiracetam
(Nra-levetiracetam)		2件: KEPPRA; Levetiracetam1件: Levetiracetam 💬1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307 💬
34 Montelukast
(Nra-montelukast)		3件: Montelukast; MONTELUKAST SODIUM; Singulair1件: Montelukast 💬1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228 💬
35 Nicotinamide
(Nrg Plus Liq)		3件: Multivitamin; Niacinamide; Nicotinamide1件: Niacinamide 💬--10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
36 Omeprazole
(Nra-omeprazole)		4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: Omeprazole 💬2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
37 Pantoprazole
(Nra-pantoprazole)		1件: PANTOPRAZOLE1件: Pantoprazole 💬2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 13, 65 💬
38 Paroxetine
(Nra-paroxetine)		1件: Paroxetine1件: Paroxetine 💬1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85 💬
39 Perindopril
(Nra-perindopril)		2件: Coversyl; Perindopril1件: Perindopril 💬1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222 💬
40 Phenylephrine
(Brontuss SF-NR)		1件: Phenylephrine1件: Phenylephrine 💬3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22 💬
41 Pregabalin
(Nra-pregabalin)		2件: Lyrica; Pregabalin1件: Pregabalin 💬4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298 💬
42 Pyridoxine
(Nrg Plus Liq)		2件: Pyridoxine; Vitamin B61件: Pyridoxine 💬--5件: 6, 93, 145, 206, 320 💬
43 Quetiapine
(Nra-quetiapine XR)		2件: Quetiapine; Seroquel1件: Quetiapine 💬2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬2件: 6, 13 💬
44 Ramipril
(Nra-ramipril)		1件: Ramipril1件: Ramipril 💬1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257 💬
45 Rosuvastatin
(Nra-rosuvastatin)		3件: Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM1件: Rosuvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
46 Sertraline
(Nra-sertraline)		1件: Sertraline1件: Sertraline 💬1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206 💬
47 Sildenafil
(Nra-sildenafil)		6件: Mysildecard; Revatio; Sildenafil; Sildenafil Citrate; SILDENAFILO; Viagra1件: Sildenafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
48 Sodium fluoride
(Nrg Apf)		1件: Sodium fluoride1件: Sodium fluoride 💬--1件: 51 💬
49 Tadalafil
(Nra-tadalafil)		4件: Adcirca; CIALIS; TADALAFIL; TADALAFILO1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210 💬
50 Telmisartan
(Nra-telmisartan)		1件: Telmisartan1件: Telmisartan 💬1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67 💬
51 Thiamine
(Nrg Plus Liq)		2件: Thiamine; Vitamin B11件: Thiamine 💬--4件: 8, 93, 145, 265 💬
52 Tramadol
(Nra-tramadol/acet)		2件: Tramadol; Ultracet1件: Tramadol 💬1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271 💬
53 Vitamin A
(Nrg Plus Liq)		1件: Vitamin A1件: Vitamin A 💬2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90 💬
54 Zinc oxide
(Face Stockholm BB Natural Beauty Balm SPF 30 Shade NR 1)		1件: Zinc oxide1件: Zinc oxide 💬--1件: 156 💬
55 Zolmitriptan
(Nra-zolmitriptan)		1件: Zolmitriptan1件: Zolmitriptan 💬2件: HTR1B,
HTR1D 💬		4件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6 💬
56 Zopiclone
(Nra-zopiclone)		1件: Zopiclone1件: Zopiclone 💬16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6 💬