Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetylcysteine 3件: Acetylcysteine; Mucomyst; N-acetylcysteine1件: D00221 --20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
2 Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells 1件: Orbcel-C---2件: 94, 95
3 Azathioprine 3件: Azathioprine; Azatioprina; Imuran2件: D00238 ,
D03033
--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
4 Bezafibrate 1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324
5 Budesonide 4件: BUDESONIDE; Entocort; Jorveza; Symbicort1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299
6 Calcium 2件: Calcio; Calcium---30件: 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
7 Capecitabine 1件: Capecitabine1件: D01223 1件: TYMS 💬4件: Antifolate resistance, Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism 💬1件: 94
8 Cenicriviroc 1件: Cenicriviroc1件: D09878 2件: CCR2,
CCR5 💬
9件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral protein interaction with cytokine and cytokine receptor 💬1件: 94
9 Cilofexor 1件: Cilofexor---2件: 93, 94
10 Cladribine 4件: 2-CdA; CLADRIBINA; CLADRIBINE; MAVENCLAD1件: D01370 1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬3件: 11, 13, 94
11 Curcumin 1件: Curcumin---11件: 2, 13, 46, 49, 67, 74, 94, 96, 97, 139, 299
12 Doconexent 1件: Docosahexaenoic acid---10件: 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
13 Erlotinib 1件: Erlotinib2件: D04023 ,
D07907
1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 94
14 Fenofibrate 1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬5件: 8, 79, 93, 94, 265
15 Metronidazole 3件: Flagyl; Metronidazol; Metronidazole3件: D00409 ,
D05016 ,
D05017
--8件: 46, 51, 63, 94, 95, 96, 97, 291
16 Minocycline 3件: Minocycline; Minocycline hydrochloride; Minomycin2件: D00850 ,
D05045
--14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
17 Mitomycin 2件: Mitomycin; Mitomycin C1件: D00208 --3件: 94, 118, 329
18 Mizoribine 2件: BREDININ; Mizoribine1件: D01392 2件: IMPDH1,
IMPDH2 💬
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224
19 norUrsodeoxycholic acid 2件: Norucholic acid; NorUrsodeoxycholic Acid---2件: 93, 94
20 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; PHENYLBUTYRATE; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
21 Potassium 1件: Potassium1件: D08403 --12件: 36, 46, 66, 67, 88, 94, 98, 115, 167, 179, 215, 235
22 Proline 1件: Proline1件: D00035 --2件: 94, 97
23 Rifaximin 3件: Rifaximin; RIFAXIMINA; Xifaxan1件: D02554 --8件: 6, 65, 93, 94, 96, 97, 99, 296
24 Rituximab 6件: MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; TRUXIMA1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬49件: 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
25 Seladelpar 1件: SELADELPAR1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94
26 Simtuzumab 2件: GS-6624; Simtuzumab---2件: 85, 94
27 Simvastatin 3件: SIMVASTATIN; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
28 Sulfasalazine 3件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine1件: D00448 --6件: 46, 86, 94, 107, 270, 271
29 Thalidomide 1件: THALIDOMIDE1件: D00754 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
30 Tretinoin 5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 3件: PML,
RARA,
RARB 💬
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
31 Ursodeoxycholic acid 4件: UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
32 Ursolic acid 1件: Ursolic acid---1件: 94
33 Vancomycin 1件: Vancomycin2件: D00212 ,
D00926
--7件: 46, 70, 94, 96, 97, 296, 299
34 Vedolizumab 2件: ENTYVIO; VEDOLIZUMAB1件: D08083 2件: ITGA4,
ITGB7 💬
15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬3件: 94, 96, 97
35 Vidofludimus 1件: Vidofludimus---5件: 13, 46, 94, 96, 97
36 Volixibat 1件: Volixibat1件: D11007 --2件: 93, 94
37 Zidovudine 3件: COMBIVIR; Retrovir; Zidovudine1件: D00413 --7件: 25, 26, 94, 135, 265, 325, 331