Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Mannitol 💬
(Tobrex (TN))		1件: Mannitol4件: Aridol; Bronchitol; Mannite; MANNITOL; --7件: 6, 13, 28, 60, 96, 113, 299 💬
2 Tobramycin 💬 1件: Tobramycin9件: Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum; --1件: 299 💬
3 Furosemide 💬
(14-PANEL TOXICOLOGY MEDICATED COLLECTION SYSTEM)		1件: Furosemide (Toxicology Medicated Collection System)2件: Furosemide; Furosemide Injection; 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 6, 86 💬
4 Itraconazole 💬
(TOLSURA)		1件: Itraconazole (Tolsura)2件: Itraconazole; Sporanox; --6件: 3, 46, 65, 96, 227, 299 💬
5 Metronidazole 💬
(METRONIDAZOLE TOPICAL CREAM)		1件: Metronidazole (Metronidazole Topical Gel)3件: Flagyl; Metronidazol; Metronidazole; --7件: 46, 51, 63, 94, 96, 97, 291 💬
6 Topiramate 💬 1件: Topiramate2件: TOPAMAX; Topiramate; 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193 💬
7 Tolterodine 💬 1件: Tolterodine1件: Tolterodine; 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53 💬
8 Botulinum toxin type A 💬 1件: Botulinum toxin type A8件: Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin; 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
9 Tolcapone 💬 1件: Tolcapone3件: Tasmar; Tolcapon; TOLCAPONE; 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127 💬
10 Tolfenamic acid 💬 1件: Tolfenamic acid1件: Tolfenamic Acid; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
11 Tolvaptan 💬 1件: Tolvaptan3件: Jinarc; Samsca; TOLVAPTAN; 1件: AVPR2 💬3件: Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 67, 72, 86, 225 💬
12 Fluocinolone acetonide 💬
(FLUOCINOLONE ACETONIDE TOPICAL)		1件: Fluocinolone acetonide (Fluocinolone Acetonide Topical)2件: Fluocinolone Acetonide; Iluvien; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90 💬
13 Tocopherol 💬 1件: Tocopherol2件: Tocoferol; Tocopherol; --6件: 13, 49, 90, 206, 257, 298 💬
14 Tocilizumab 💬 1件: Tocilizumab3件: Actemra; ROACTEMRA; TOCILIZUMAB; 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
15 Rimabotulinumtoxin B 💬
(Botulinum toxin type B (JAN))		1件: Botulinum toxin type B3件: Botulinum toxin type B; MYOBLOC; NEUROBLOC; 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬4件: 2, 6, 13, 51 💬
16 Insulin glargine 💬
(TOUJEO)		1件: Insulin glargine (Toujeo Doublestar)1件: Insulin glargine; 1件: INSR 💬22件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 299 💬
17 Temsirolimus 💬
(Torisel (TN))		1件: Temsirolimus (Torisel)1件: Temsirolimus; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬1件: 13 💬
18 Tocophersolan 💬 1件: Tocofersolan1件: VEDROP; --1件: 299 💬
19 Toralizumab 💬 1件: Toralizumab1件: Anti-CD40L; 1件: CD40LG 💬14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬1件: 63 💬
20 Atomoxetine 💬
(Tomoxetine)		1件: Atomoxetine (Tomoxetinum)2件: Atomoxetine; Strattera; 1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17 💬
21 Ketorolac 💬
(Toradol (TN))		1件: Ketorolac (Toradol Tab 10mg)2件: Ketorolac; Ketorolac Tromethamine; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬2件: 70, 226 💬
22 Tolperisone 💬 1件: Tolperisone1件: Tolperisone; --1件: 13 💬
23 Topotecan 💬 1件: Topotecan1件: Topotecan; 1件: TOP1 💬1件: 💬1件: 25 💬
24 Tedizolid 💬
(Torezolid)		1件: Tedizolid (Torezolid)1件: Tedizolid; --1件: 299 💬
25 Tofacitinib 💬 1件: Tofacitinib4件: Tasocitinib; Tofacitinib; XELJANZ; Xeljanz XR; 4件: JAK1,
JAK2,
JAK3,
TYK2 💬		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
26 Tozadenant 💬 1件: Tozadenant1件: TOZADENANT; 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6 💬
27 Tofersen 💬 1件: Tofersen1件: Tofersen; 1件: SOD1 💬8件: Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬1件: 2 💬
28 Tozinameran 💬 1件: Tozinameran2件: Comirnaty; Tozinameran; --5件: 13, 46, 51, 53, 299 💬