Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Glutamine 💬1件: L-Glutamine2件: Glutamine; L-Glutamine--8件: 87, 89, 96, 97, 113, 222, 245, 299 💬
2 Mannitol 💬1件: Mannitol4件: Aridol; Bronchitol; Mannite; Mannitol--7件: 6, 13, 28, 60, 96, 113, 299 💬
3 Testosterone 💬1件: Testosterone1件: Testosterone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬8件: 1, 2, 3, 13, 60, 76, 78, 113 💬
4 Tacrolimus 💬1件: Tacrolimus2件: Prograf; Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
5 Aspirin 💬1件: Acetylsalicylic acid2件: Acetylsalicylic Acid; Aspirin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
6 Calcifediol 💬1件: Calcifediol2件: 25-Hydroxyvitamin D3; CALCIFEDIOL1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 113, 299 💬
7 Ibuprofen 💬1件: Ibuprofen2件: Ibuprofen; IBUPROFEN 200MG2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299 💬
8 Cyclosporine 💬1件: Cyclosporine10件: CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; RESTASIS5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
9 Carvedilol 💬1件: Carvedilol1件: Carvedilol5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 86, 113, 210 💬
10 Cosyntropin 💬1件: Tetracosactide4件: Cosyntropin; Synacthen Depot; TETRACOSACTIDE; Tetracosactrin1件: MC2R 💬 5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222 💬
11 Isosorbide 💬1件: Isosorbide1件: Isosorbide--1件: 113 💬
12 Lisinopril 💬1件: Lisinopril2件: Lisinopril; Zestril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
13 Ramipril 💬1件: Ramipril1件: Ramipril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257 💬
14 Spironolactone 💬1件: Spironolactone1件: SPIRONOLACTONE1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225 💬
15 Prednisolone 💬1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
16 Prednisone 💬1件: Prednisone3件: PREDNISONA; Prednisone; RAYOS1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
17 Pentoxifylline 💬1件: Pentoxifylline1件: Pentoxifylline--12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
18 Dexmedetomidine 💬1件: Dexmedetomidine4件: Dexdor; DEXMEDETOMIDINA; DEXMEDETOMIDINE; DEXMEDETOMIDINE HYDROCHLORIDE3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
19 Isosorbide dinitrate 💬1件: Isosorbide dinitrate2件: Isosorbide; ISOSORBIDE DINITRATE--1件: 113 💬
20 Botulinum toxin type A 💬1件: Botulinum toxin type A8件: BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin1件: SNAP25 💬 2件: Insulin secretion, Synaptic vesicle cycle 💬14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
21 Testosterone enanthate 💬1件: Testosterone enanthate1件: Testosterone Enanthate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
22 Testosterone propionate 💬1件: Testosterone propionate1件: Testosterone propionate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
23 Ubidecarenone 💬1件: Ubidecarenone3件: Coenzyme Q-10; Coenzyme Q10; CoQ10--12件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
24 Eplerenone 💬1件: Eplerenone1件: Eplerenone1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215 💬
25 Idebenone 💬1件: Idebenone2件: Idebenone; Raxone--6件: 6, 8, 13, 18, 113, 302 💬
26 Oxatomide 💬1件: Oxatomide1件: Oxatomide1件: ALOX5 💬 6件: Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬1件: 113 💬
27 Modafinil 💬1件: Modafinil2件: MODAFINIL; Provigil--5件: 6, 13, 49, 93, 113 💬
28 Tadalafil 💬1件: Tadalafil4件: Adcirca; CIALIS; TADALAFIL; TADALAFILO1件: PDE5A 💬 3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210 💬
29 Tranilast 💬1件: Tranilast1件: Tranilast--4件: 46, 84, 106, 113 💬
30 Albuterol 💬1件: Salbutamol3件: Albuterol; SALBUTAMOL; Ventolin1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
31 Nitric acid 💬1件: Nitrate1件: Nitrate--4件: 58, 67, 113, 299 💬
32 Bisoprolol 💬1件: Bisoprolol2件: Bisoprolol; Bisoprolol Fumarate1件: ADRB1 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 58, 67, 86, 113 💬
33 Metoprolol 💬1件: Metoprolol2件: Metoprolol; METOPROLOL SUCCINATE1件: ADRB1 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226 💬
34 Arginine 💬2件: Arginine,
L-arginine		6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene--12件: 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299 💬
35 Filgrastim 💬1件: Filgrastim7件: Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; NEUPOGEN; TEVAGRASTIM; ZARZIO1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
36 Deflazacort 💬1件: Deflazacort1件: Deflazacort1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 30, 113 💬
37 Perindopril 💬1件: Perindopril2件: Coversyl; Perindopril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222 💬
38 Ifetroban 💬1件: Ifetroban1件: Ifetroban1件: TBXA2R 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬2件: 85, 113 💬
39 Lonafarnib 💬1件: Lonafarnib1件: Lonafarnib2件: FNTA,
FNTB 💬 		1件: Terpenoid backbone biosynthesis 💬2件: 113, 333 💬
40 Metformin 💬1件: Metformin5件: Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
41 Methylphenidate 💬1件: Methylphenidate3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin2件: SLC6A2,
SLC6A3 💬 		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206 💬
42 Nebivolol 💬1件: Nebivolol1件: Nebivolol1件: ADRB1 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167 💬
43 Ranolazine 💬1件: Ranolazine3件: RANEXA; Ranolazina; Ranolazine--6件: 2, 58, 86, 96, 113, 114 💬
44 Stamulumab 💬1件: Stamulumab1件: MYO-0291件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 113 💬
45 Pemirolast 💬1件: Pemirolast1件: PEMIROLAST--1件: 113 💬
46 Enalapril 💬1件: Enalapril2件: Enalapril; Enalapril Maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 19, 46, 66, 113, 210, 222 💬
47 Esomeprazole 💬1件: Esomeprazole3件: Esomeprazole; Nexium; Omeprazole2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
48 Gentamicin 💬1件: Gentamicin2件: Gentamicin; Gentamicin Sulfate--3件: 36, 113, 299 💬
49 Icosapent 💬1件: Icosapent2件: Eicosapentaenoic acid; Icosapent--7件: 8, 49, 96, 97, 296, 297, 338 💬
50 Ketamine 💬1件: Ketamine2件: Ketamine; NMDA5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬6件: 6, 13, 70, 113, 156, 215 💬
51 Lisinopril 💬1件: Lisinopril2件: Lisinopril; ZESTRIL1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
52 Losartan 💬1件: Losartan3件: Cozaar; Losartan; LOSARTAN POTASSIUM1件: AGTR1 💬 16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
53 Mexiletine 💬1件: Mexiletine4件: Mexiletina; Mexiletine; Mexitil; Namuscla5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 1, 2, 10, 113, 114 💬
54 Moxifloxacin 💬1件: Moxifloxacin2件: Moxifloxacin; Moxifloxacin Hydrochloride--9件: 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
55 Prasterone 💬1件: Prasterone3件: Dehydroepiandrosterone; DHEA; Prasterone3件: AR,
ESR1,
ESR2 💬 		12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬6件: 49, 53, 83, 86, 96, 113 💬
56 Risedronic acid 💬1件: Risedronic acid3件: Risedronate; RISEDRONATE SODIUM; Risedronic acid1件: FDPS 💬 4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
57 Sildenafil 💬1件: Sildenafil6件: Mysildecard; Revatio; SILDENAFIL; SILDENAFIL CITRATE; SILDENAFILO; Viagra1件: PDE5A 💬 3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
58 Tacrolimus 💬1件: Tacrolimus2件: Prograf; Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
59 Tamoxifen 💬1件: Tamoxifen2件: TAMOXIFEN; TAMOXIFEN CITRATE2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬3件: 2, 113, 227 💬
60 Testosterone decanoate 💬1件: Testosterone decanoate1件: Testosterone decanoate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
61 Testosterone phenylpropionate 💬1件: Testosterone phenylpropionate1件: Testosterone phenylpropionate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
62 Canakinumab 💬1件: Canakinumab2件: CANAKINUMAB; Ilaris1件: IL1B 💬 44件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
63 Ataluren 💬1件: Ataluren2件: ATALUREN; Translarna--6件: 19, 113, 140, 246, 299, 329 💬
64 Losmapimod 💬1件: Losmapimod1件: LOSMAPIMOD4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬 		62件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬2件: 113, 222 💬
65 Eteplirsen 💬1件: Eteplirsen2件: ETEPLIRSEN; Exondys 511件: DMD 💬 4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
66 Drisapersen 💬1件: Drisapersen1件: Drisapersen1件: DMD 💬 4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
67 Pitolisant 💬1件: Pitolisant1件: Pitolisant1件: HRH3 💬 1件: Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193 💬
68 Pamrevlumab 💬1件: Pamrevlumab1件: PAMREVLUMAB1件: CCN2 💬 2件: Apelin signaling pathway, Hippo signaling pathway 💬2件: 85, 113 💬
69 Vamorolone 💬1件: Vamorolone1件: Vamorolone1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 97, 113 💬
70 Domagrozumab 💬1件: Domagrozumab1件: PF-062526161件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 113 💬
71 Viltolarsen 💬1件: Viltolarsen1件: VILTOLARSEN1件: DMD 💬 4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
72 Golodirsen 💬1件: Golodirsen2件: GOLODIRSEN; Vyondys 531件: DMD 💬 4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
73 Casimersen 💬1件: Casimersen1件: CASIMERSEN1件: DMD 💬 4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113 💬
74 Edasalonexent 💬1件: Edasalonexent1件: EDASALONEXENT1件: RELA 💬 76件: AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬1件: 113 💬
75 Bocidelpar 💬1件: Bocidelpar1件: Bocidelpar1件: PPARG 💬 11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 113 💬